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Functional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes.
Bushell E, Gomes AR, Sanderson T, Anar B, Girling G, Herd C, Metcalf T, Modrzynska K, Schwach F, Martin RE, Mather MW, McFadden GI, Parts L, Rutledge GG, Vaidya AB, Wengelnik K, Rayner JC, Billker O. Bushell E, et al. Among authors: metcalf t. Cell. 2017 Jul 13;170(2):260-272.e8. doi: 10.1016/j.cell.2017.06.030. Cell. 2017. PMID: 28708996 Free PMC article.
Genome-Scale Identification of Essential Metabolic Processes for Targeting the Plasmodium Liver Stage.
Stanway RR, Bushell E, Chiappino-Pepe A, Roques M, Sanderson T, Franke-Fayard B, Caldelari R, Golomingi M, Nyonda M, Pandey V, Schwach F, Chevalley S, Ramesar J, Metcalf T, Herd C, Burda PC, Rayner JC, Soldati-Favre D, Janse CJ, Hatzimanikatis V, Billker O, Heussler VT. Stanway RR, et al. Among authors: metcalf t. Cell. 2019 Nov 14;179(5):1112-1128.e26. doi: 10.1016/j.cell.2019.10.030. Cell. 2019. PMID: 31730853 Free PMC article.
Systematic Identification of Plasmodium Falciparum Sporozoite Membrane Protein Interactions Reveals an Essential Role for the p24 Complex in Host Infection.
Knöckel J, Dundas K, Yang ASP, Galaway F, Metcalf T, Gemert GV, Sauerwein RW, Rayner JC, Billker O, Wright GJ. Knöckel J, et al. Among authors: metcalf t. Mol Cell Proteomics. 2021;20:100038. doi: 10.1074/mcp.RA120.002432. Epub 2021 Jan 27. Mol Cell Proteomics. 2021. PMID: 33515807 Free PMC article.
Antibody-independent mechanisms regulate the establishment of chronic Plasmodium infection.
Brugat T, Reid AJ, Lin J, Cunningham D, Tumwine I, Kushinga G, McLaughlin S, Spence P, Böhme U, Sanders M, Conteh S, Bushell E, Metcalf T, Billker O, Duffy PE, Newbold C, Berriman M, Langhorne J. Brugat T, et al. Among authors: metcalf t. Nat Microbiol. 2017 Feb 6;2:16276. doi: 10.1038/nmicrobiol.2016.276. Nat Microbiol. 2017. PMID: 28165471 Free PMC article.
Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes.
White JK, Gerdin AK, Karp NA, Ryder E, Buljan M, Bussell JN, Salisbury J, Clare S, Ingham NJ, Podrini C, Houghton R, Estabel J, Bottomley JR, Melvin DG, Sunter D, Adams NC; Sanger Institute Mouse Genetics Project; Tannahill D, Logan DW, Macarthur DG, Flint J, Mahajan VB, Tsang SH, Smyth I, Watt FM, Skarnes WC, Dougan G, Adams DJ, Ramirez-Solis R, Bradley A, Steel KP. White JK, et al. Cell. 2013 Jul 18;154(2):452-64. doi: 10.1016/j.cell.2013.06.022. Cell. 2013. PMID: 23870131 Free PMC article.
138 results