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207 results

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A multicenter, randomized phase 2 study to establish combinations of CBP501, cisplatin and nivolumab for ≥3rd-line treatment of patients with advanced pancreatic adenocarcinoma.
Enzler T, Nguyen A, Misleh J, Cline VJ, Johns M, Shumway N, Paulson S, Siegel R, Larson T, Messersmith W, Richards D, Chaves J, Pierce E, Zalupski M, Sahai V, Orr D, Ruste SA, Haun A, Kawabe T. Enzler T, et al. Among authors: messersmith w. Eur J Cancer. 2024 Apr;201:113950. doi: 10.1016/j.ejca.2024.113950. Epub 2024 Feb 22. Eur J Cancer. 2024. PMID: 38422585 Free article. Clinical Trial.
Adjuvant nab-Paclitaxel + Gemcitabine in Resected Pancreatic Ductal Adenocarcinoma: Results From a Randomized, Open-Label, Phase III Trial.
Tempero MA, Pelzer U, O'Reilly EM, Winter J, Oh DY, Li CP, Tortora G, Chang HM, Lopez CD, Bekaii-Saab T, Ko AH, Santoro A, Park JO, Noel MS, Frassineti GL, Shan YS, Dean A, Riess H, Van Cutsem E, Berlin J, Philip P, Moore M, Goldstein D, Tabernero J, Li M, Ferrara S, Le Bruchec Y, Zhang G, Lu B, Biankin AV, Reni M; APACT Investigators. Tempero MA, et al. J Clin Oncol. 2023 Apr 10;41(11):2007-2019. doi: 10.1200/JCO.22.01134. Epub 2022 Dec 15. J Clin Oncol. 2023. PMID: 36521097 Free PMC article. Clinical Trial.
A Phase Ib Expansion Cohort Evaluating Aurora A Kinase Inhibitor Alisertib and Dual TORC1/2 Inhibitor Sapanisertib in Patients with Advanced Solid Tumors.
Davis SL, Messersmith WA, Purcell WT, Lam ET, Corr BR, Leal AD, Lieu CH, O'Bryant CL, Smoots SG, Dus ED, Jordan KR, Serkova NJ, Pitts TM, Diamond JR. Davis SL, et al. Among authors: messersmith wa. Cancers (Basel). 2024 Apr 10;16(8):1456. doi: 10.3390/cancers16081456. Cancers (Basel). 2024. PMID: 38672538 Free PMC article.
Pancreatic Ductal Adenocarcinoma Cells Regulate NLRP3 Activation to Generate a Tolerogenic Microenvironment.
Amo-Aparicio J, Dominguez A, Atif SM, Dinarello A, Azam T, Alula KM, Piper M, Lieu CH, Lentz RW, Leal AD, Bagby SM, Messersmith WA, Karam SD, Dinarello CA, Pitts TM, Marchetti C. Amo-Aparicio J, et al. Among authors: messersmith wa. Cancer Res Commun. 2023 Sep 20;3(9):1899-1911. doi: 10.1158/2767-9764.CRC-23-0065. Cancer Res Commun. 2023. PMID: 37772994 Free PMC article.
Examination of Wnt signaling as a therapeutic target for pancreatic ductal adenocarcinoma (PDAC) using a pancreatic tumor organoid library (PTOL).
Hawkins HJ, Yacob BW, Brown ME, Goldstein BR, Arcaroli JJ, Bagby SM, Hartman SJ, Macbeth M, Goodspeed A, Danhorn T, Lentz RW, Lieu CH, Leal AD, Messersmith WA, Dempsey PJ, Pitts TM. Hawkins HJ, et al. Among authors: messersmith wa. PLoS One. 2024 Apr 10;19(4):e0298808. doi: 10.1371/journal.pone.0298808. eCollection 2024. PLoS One. 2024. PMID: 38598488 Free PMC article.
Avelumab or talazoparib in combination with binimetinib in metastatic pancreatic ductal adenocarcinoma: dose-finding results from phase Ib of the JAVELIN PARP MEKi trial.
Rodon Ahnert J, Tan DS, Garrido-Laguna I, Harb W, Bessudo A, Beck JT, Rottey S, Bahary N, Kotecki N, Zhu Z, Deng S, Kowalski K, Wei C, Pathan N, Laliberte RJ, Messersmith WA. Rodon Ahnert J, et al. Among authors: messersmith wa. ESMO Open. 2023 Aug;8(4):101584. doi: 10.1016/j.esmoop.2023.101584. Epub 2023 Jun 26. ESMO Open. 2023. PMID: 37379764 Free PMC article. Clinical Trial.
HER2-Positive Metastatic Colorectal Cancer.
Robinson HR, Messersmith WA, Lentz RW. Robinson HR, et al. Among authors: messersmith wa. Curr Treat Options Oncol. 2024 May;25(5):585-604. doi: 10.1007/s11864-024-01183-7. Epub 2024 Mar 28. Curr Treat Options Oncol. 2024. PMID: 38539034 Review.
Advances in the management of pancreatic cancer.
Del Chiaro M, Sugawara T, Karam SD, Messersmith WA. Del Chiaro M, et al. Among authors: messersmith wa. BMJ. 2023 Dec 13;383:e073995. doi: 10.1136/bmj-2022-073995. BMJ. 2023. PMID: 38164628 Review.
207 results