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Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1.
Verhaak RG, Hoadley KA, Purdom E, Wang V, Qi Y, Wilkerson MD, Miller CR, Ding L, Golub T, Mesirov JP, Alexe G, Lawrence M, O'Kelly M, Tamayo P, Weir BA, Gabriel S, Winckler W, Gupta S, Jakkula L, Feiler HS, Hodgson JG, James CD, Sarkaria JN, Brennan C, Kahn A, Spellman PT, Wilson RK, Speed TP, Gray JW, Meyerson M, Getz G, Perou CM, Hayes DN; Cancer Genome Atlas Research Network. Verhaak RG, et al. Among authors: mesirov jp. Cancer Cell. 2010 Jan 19;17(1):98-110. doi: 10.1016/j.ccr.2009.12.020. Cancer Cell. 2010. PMID: 20129251 Free PMC article.
Molecular classification of multiple tumor types.
Yeang CH, Ramaswamy S, Tamayo P, Mukherjee S, Rifkin RM, Angelo M, Reich M, Lander E, Mesirov J, Golub T. Yeang CH, et al. Bioinformatics. 2001;17 Suppl 1:S316-22. doi: 10.1093/bioinformatics/17.suppl_1.s316. Bioinformatics. 2001. PMID: 11473023
Chemosensitivity prediction by transcriptional profiling.
Staunton JE, Slonim DK, Coller HA, Tamayo P, Angelo MJ, Park J, Scherf U, Lee JK, Reinhold WO, Weinstein JN, Mesirov JP, Lander ES, Golub TR. Staunton JE, et al. Among authors: mesirov jp. Proc Natl Acad Sci U S A. 2001 Sep 11;98(19):10787-92. doi: 10.1073/pnas.191368598. Proc Natl Acad Sci U S A. 2001. PMID: 11553813 Free PMC article.
Multiclass cancer diagnosis using tumor gene expression signatures.
Ramaswamy S, Tamayo P, Rifkin R, Mukherjee S, Yeang CH, Angelo M, Ladd C, Reich M, Latulippe E, Mesirov JP, Poggio T, Gerald W, Loda M, Lander ES, Golub TR. Ramaswamy S, et al. Among authors: mesirov jp. Proc Natl Acad Sci U S A. 2001 Dec 18;98(26):15149-54. doi: 10.1073/pnas.211566398. Epub 2001 Dec 11. Proc Natl Acad Sci U S A. 2001. PMID: 11742071 Free PMC article.
Prediction of central nervous system embryonal tumour outcome based on gene expression.
Pomeroy SL, Tamayo P, Gaasenbeek M, Sturla LM, Angelo M, McLaughlin ME, Kim JY, Goumnerova LC, Black PM, Lau C, Allen JC, Zagzag D, Olson JM, Curran T, Wetmore C, Biegel JA, Poggio T, Mukherjee S, Rifkin R, Califano A, Stolovitzky G, Louis DN, Mesirov JP, Lander ES, Golub TR. Pomeroy SL, et al. Among authors: mesirov jp. Nature. 2002 Jan 24;415(6870):436-42. doi: 10.1038/415436a. Nature. 2002. PMID: 11807556
PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes.
Mootha VK, Lindgren CM, Eriksson KF, Subramanian A, Sihag S, Lehar J, Puigserver P, Carlsson E, Ridderstråle M, Laurila E, Houstis N, Daly MJ, Patterson N, Mesirov JP, Golub TR, Tamayo P, Spiegelman B, Lander ES, Hirschhorn JN, Altshuler D, Groop LC. Mootha VK, et al. Among authors: mesirov jp. Nat Genet. 2003 Jul;34(3):267-73. doi: 10.1038/ng1180. Nat Genet. 2003. PMID: 12808457
147 results