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Targeting the MAPK Signaling Pathway in Cancer: Promising Preclinical Activity with the Novel Selective ERK1/2 Inhibitor BVD-523 (Ulixertinib).
Germann UA, Furey BF, Markland W, Hoover RR, Aronov AM, Roix JJ, Hale M, Boucher DM, Sorrell DA, Martinez-Botella G, Fitzgibbon M, Shapiro P, Wick MJ, Samadani R, Meshaw K, Groover A, DeCrescenzo G, Namchuk M, Emery CM, Saha S, Welsch DJ. Germann UA, et al. Among authors: meshaw k. Mol Cancer Ther. 2017 Nov;16(11):2351-2363. doi: 10.1158/1535-7163.MCT-17-0456. Epub 2017 Sep 22. Mol Cancer Ther. 2017. PMID: 28939558
Novel patient-derived xenograft mouse model for pancreatic acinar cell carcinoma demonstrates single agent activity of oxaliplatin.
Hall JC, Marlow LA, Mathias AC, Dawson LK, Durham WF, Meshaw KA, Mullin RJ, Synnott AJ, Small DL, Krishna M, von Hoff D, Schüler J, Hart SN, Couch FJ, Colon-Otero G, Copland JA. Hall JC, et al. Among authors: meshaw ka. J Transl Med. 2016 May 10;14(1):129. doi: 10.1186/s12967-016-0875-z. J Transl Med. 2016. PMID: 27165126 Free PMC article.
Identification of cell surface and secreted proteins essential for tumor cell survival using a genetic suppressor element screen.
Gelman MS, Ye XK, Stull R, Suhy D, Jin L, Ng D, Than B, Ji M, Pan A, Perez P, Sun Y, Yeung P, Garcia LM, Harte R, Lu Y, Lamar E, Tavassoli R, Kennedy S, Osborn S, Chin DJ, Meshaw K, Holzmayer TA, Axenovich SA, Abo A. Gelman MS, et al. Among authors: meshaw k. Oncogene. 2004 Oct 21;23(49):8158-70. doi: 10.1038/sj.onc.1208054. Oncogene. 2004. PMID: 15361835
Alpha-lactalbumin as a modulator of mammary cellular activity.
Alston-Mills B, Hepler CD, Sternhagen L, Allen JC, Meshaw KA. Alston-Mills B, et al. Among authors: meshaw ka. In Vitro Cell Dev Biol Anim. 1998 Nov-Dec;34(10):747-50. doi: 10.1007/s11626-998-0026-9. In Vitro Cell Dev Biol Anim. 1998. PMID: 9870521 No abstract available.