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Candida tropicalis antifungal cross-resistance is related to different azole target (Erg11p) modifications.
Forastiero A, Mesa-Arango AC, Alastruey-Izquierdo A, Alcazar-Fuoli L, Bernal-Martinez L, Pelaez T, Lopez JF, Grimalt JO, Gomez-Lopez A, Cuesta I, Zaragoza O, Mellado E. Forastiero A, et al. Antimicrob Agents Chemother. 2013 Oct;57(10):4769-81. doi: 10.1128/AAC.00477-13. Epub 2013 Jul 22. Antimicrob Agents Chemother. 2013. PMID: 23877676 Free PMC article.
The production of reactive oxygen species is a universal action mechanism of Amphotericin B against pathogenic yeasts and contributes to the fungicidal effect of this drug.
Mesa-Arango AC, Trevijano-Contador N, Román E, Sánchez-Fresneda R, Casas C, Herrero E, Argüelles JC, Pla J, Cuenca-Estrella M, Zaragoza O. Mesa-Arango AC, et al. Antimicrob Agents Chemother. 2014 Nov;58(11):6627-38. doi: 10.1128/AAC.03570-14. Epub 2014 Aug 25. Antimicrob Agents Chemother. 2014. PMID: 25155595 Free PMC article.
34 results