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Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs.
Steinebach C, Bricelj A, Murgai A, Sosič I, Bischof L, Ng YLD, Heim C, Maiwald S, Proj M, Voget R, Feller F, Košmrlj J, Sapozhnikova V, Schmidt A, Zuleeg MR, Lemnitzer P, Mertins P, Hansen FK, Gütschow M, Krönke J, Hartmann MD. Steinebach C, et al. Among authors: mertins p. J Med Chem. 2023 Nov 9;66(21):14513-14543. doi: 10.1021/acs.jmedchem.3c00851. Epub 2023 Oct 30. J Med Chem. 2023. PMID: 37902300 Free PMC article.
Carm1-arginine methylation of the transcription factor C/EBPα regulates transdifferentiation velocity.
Torcal Garcia G, Kowenz-Leutz E, Tian TV, Klonizakis A, Lerner J, De Andres-Aguayo L, Sapozhnikova V, Berenguer C, Carmona MP, Casadesus MV, Bulteau R, Francesconi M, Peiro S, Mertins P, Zaret K, Leutz A, Graf T. Torcal Garcia G, et al. Among authors: mertins p. Elife. 2023 Jun 27;12:e83951. doi: 10.7554/eLife.83951. Elife. 2023. PMID: 37365888 Free PMC article.
Longitudinal effects of elexacaftor/tezacaftor/ivacaftor on sputum viscoelastic properties, airway infection and inflammation in patients with cystic fibrosis.
Schaupp L, Addante A, Völler M, Fentker K, Kuppe A, Bardua M, Duerr J, Piehler L, Röhmel J, Thee S, Kirchner M, Ziehm M, Lauster D, Haag R, Gradzielski M, Stahl M, Mertins P, Boutin S, Graeber SY, Mall MA. Schaupp L, et al. Among authors: mertins p. Eur Respir J. 2023 Aug 3;62(2):2202153. doi: 10.1183/13993003.02153-2022. Print 2023 Aug. Eur Respir J. 2023. PMID: 37414422
Pan-claudin family interactome analysis reveals shared and specific interactions.
Suarez-Artiles L, Breiderhoff T, Girardello R, Gonschior H, Rodius S, Lesur A, Reimer U, Ramberger E, Perez-Hernandez D, Müller D, Mertins P, Dittmar G. Suarez-Artiles L, et al. Among authors: mertins p. Cell Rep. 2022 Nov 8;41(6):111588. doi: 10.1016/j.celrep.2022.111588. Cell Rep. 2022. PMID: 36351382 Free article.
Frequent ZNF217 mutations lead to transcriptional deregulation of interferon signal transduction via altered chromatin accessibility in B cell lymphoma.
Briest F, Noerenberg D, Hennch C, Yoshida K, Hablesreiter R, Nimo J, Sasca D, Kirchner M, Mansouri L, Inoue Y, Wiegand L, Staiger AM, Casadei B, Korkolopoulou P, Weiner J, Lopez-Guillermo A, Warth A, Schneider T, Nagy Á, Klapper W, Hummel M, Kanellis G, Anagnostopoulos I, Mertins P, Bullinger L, Rosenquist R, Vassilakopoulos TP, Ott G, Ogawa S, Damm F. Briest F, et al. Among authors: mertins p. Leukemia. 2023 Nov;37(11):2237-2249. doi: 10.1038/s41375-023-02013-9. Epub 2023 Aug 30. Leukemia. 2023. PMID: 37648814 Free PMC article.
123 results