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Cyclin-Dependent Kinase 18 Controls Trafficking of Aquaporin-2 and Its Abundance through Ubiquitin Ligase STUB1, Which Functions as an AKAP.
Dema A, Faust D, Lazarow K, Wippich M, Neuenschwander M, Zühlke K, Geelhaar A, Pallien T, Hallscheidt E, Eichhorst J, Wiesner B, Černecká H, Popp O, Mertins P, Dittmar G, von Kries JP, Klussmann E. Dema A, et al. Among authors: mertins p. Cells. 2020 Mar 10;9(3):673. doi: 10.3390/cells9030673. Cells. 2020. PMID: 32164329 Free PMC article.
Integrated Proteogenomic Characterization of Human High-Grade Serous Ovarian Cancer.
Zhang H, Liu T, Zhang Z, Payne SH, Zhang B, McDermott JE, Zhou JY, Petyuk VA, Chen L, Ray D, Sun S, Yang F, Chen L, Wang J, Shah P, Cha SW, Aiyetan P, Woo S, Tian Y, Gritsenko MA, Clauss TR, Choi C, Monroe ME, Thomas S, Nie S, Wu C, Moore RJ, Yu KH, Tabb DL, Fenyö D, Bafna V, Wang Y, Rodriguez H, Boja ES, Hiltke T, Rivers RC, Sokoll L, Zhu H, Shih IM, Cope L, Pandey A, Zhang B, Snyder MP, Levine DA, Smith RD, Chan DW, Rodland KD; CPTAC Investigators. Zhang H, et al. Cell. 2016 Jul 28;166(3):755-765. doi: 10.1016/j.cell.2016.05.069. Epub 2016 Jun 29. Cell. 2016. PMID: 27372738 Free PMC article.
The IκB kinase complex is a regulator of mRNA stability.
Mikuda N, Kolesnichenko M, Beaudette P, Popp O, Uyar B, Sun W, Tufan AB, Perder B, Akalin A, Chen W, Mertins P, Dittmar G, Hinz M, Scheidereit C. Mikuda N, et al. Among authors: mertins p. EMBO J. 2018 Dec 14;37(24):e98658. doi: 10.15252/embj.201798658. Epub 2018 Nov 22. EMBO J. 2018. PMID: 30467221 Free PMC article.
USP15 Deubiquitinase Safeguards Hematopoiesis and Genome Integrity in Hematopoietic Stem Cells and Leukemia Cells.
van den Berk P, Lancini C, Company C, Serresi M, Sanchez-Bailon MP, Hulsman D, Pritchard C, Song JY, Schmitt MJ, Tanger E, Popp O, Mertins P, Huijbers IJ, Jacobs H, van Lohuizen M, Gargiulo G, Citterio E. van den Berk P, et al. Among authors: mertins p. Cell Rep. 2020 Dec 29;33(13):108533. doi: 10.1016/j.celrep.2020.108533. Cell Rep. 2020. PMID: 33378683 Free PMC article.
YAP and β-Catenin Cooperate to Drive Oncogenesis in Basal Breast Cancer.
Quinn HM, Vogel R, Popp O, Mertins P, Lan L, Messerschmidt C, Landshammer A, Lisek K, Château-Joubert S, Marangoni E, Koren E, Fuchs Y, Birchmeier W. Quinn HM, et al. Among authors: mertins p. Cancer Res. 2021 Apr 15;81(8):2116-2127. doi: 10.1158/0008-5472.CAN-20-2801. Epub 2021 Feb 11. Cancer Res. 2021. PMID: 33574090
The newly identified MEK1 tyrosine phosphorylation target MACC1 is druggable by approved MEK1 inhibitors to restrict colorectal cancer metastasis.
Kobelt D, Perez-Hernandez D, Fleuter C, Dahlmann M, Zincke F, Smith J, Migotti R, Popp O, Burock S, Walther W, Dittmar G, Mertins P, Stein U. Kobelt D, et al. Among authors: mertins p. Oncogene. 2021 Aug;40(34):5286-5301. doi: 10.1038/s41388-021-01917-z. Epub 2021 Jul 10. Oncogene. 2021. PMID: 34247190 Free PMC article.
Peritoneal metastasis of colorectal cancer (pmCRC): identification of predictive molecular signatures by a novel preclinical platform of matching pmCRC PDX/PD3D models.
Dahlmann M, Gambara G, Brzezicha B, Popp O, Pachmayr E, Wedeken L, Pflaume A, Mokritzkij M, Gül-Klein S, Brandl A, Schweiger-Eisbacher C, Mertins P, Hoffmann J, Keilholz U, Walther W, Regenbrecht C, Rau B, Stein U. Dahlmann M, et al. Among authors: mertins p. Mol Cancer. 2021 Oct 21;20(1):129. doi: 10.1186/s12943-021-01430-7. Mol Cancer. 2021. PMID: 34670579 Free PMC article. No abstract available.
123 results