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Page 1
Cloning a profibrotic stem cell variant in idiopathic pulmonary fibrosis.
Wang S, Rao W, Hoffman A, Lin J, Li J, Lin T, Liew AA, Vincent M, Mertens TCJ, Karmouty-Quintana H, Crum CP, Metersky ML, Schwartz DA, Davies PJA, Stephan C, Jyothula SSK, Sheshadri A, Suarez EE, Huang HJ, Engelhardt JF, Dickey BF, Parekh KR, McKeon FD, Xian W. Wang S, et al. Among authors: mertens tcj. Sci Transl Med. 2023 Apr 26;15(693):eabp9528. doi: 10.1126/scitranslmed.abp9528. Epub 2023 Apr 26. Sci Transl Med. 2023. PMID: 37099633 Free PMC article.
Regenerative Metaplastic Clones in COPD Lung Drive Inflammation and Fibrosis.
Rao W, Wang S, Duleba M, Niroula S, Goller K, Xie J, Mahalingam R, Neupane R, Liew AA, Vincent M, Okuda K, O'Neal WK, Boucher RC, Dickey BF, Wechsler ME, Ibrahim O, Engelhardt JF, Mertens TCJ, Wang W, Jyothula SSK, Crum CP, Karmouty-Quintana H, Parekh KR, Metersky ML, McKeon FD, Xian W. Rao W, et al. Among authors: mertens tcj. Cell. 2020 May 14;181(4):848-864.e18. doi: 10.1016/j.cell.2020.03.047. Epub 2020 Apr 15. Cell. 2020. PMID: 32298651 Free PMC article.
Sine oculis homeobox homolog 1 plays a critical role in pulmonary fibrosis.
Wilson C, Mertens TC, Shivshankar P, Bi W, Collum SD, Wareing N, Ko J, Weng T, Naikawadi RP, Wolters PJ, Maire P, Jyothula SS, Thandavarayan RA, Ren D, Elrod ND, Wagner EJ, Huang HJ, Dickey BF, Ford HL, Karmouty-Quintana H. Wilson C, et al. JCI Insight. 2022 May 23;7(10):e142984. doi: 10.1172/jci.insight.142984. JCI Insight. 2022. PMID: 35420997 Free PMC article.
Cleavage factor 25 deregulation contributes to pulmonary fibrosis through alternative polyadenylation.
Weng T, Ko J, Masamha CP, Xia Z, Xiang Y, Chen NY, Molina JG, Collum S, Mertens TC, Luo F, Philip K, Davies J, Huang J, Wilson C, Thandavarayan RA, Bruckner BA, Jyothula SS, Volcik KA, Li L, Han L, Li W, Assassi S, Karmouty-Quintana H, Wagner EJ, Blackburn MR. Weng T, et al. J Clin Invest. 2019 Feb 28;129(5):1984-1999. doi: 10.1172/JCI122106. Print 2019 May 1. J Clin Invest. 2019. PMID: 30830875 Free PMC article.
Transcriptomic and Epigenetic Profiling of Fibroblasts in Idiopathic Pulmonary Fibrosis.
Hanmandlu A, Zhu L, Mertens TCJ, Collum S, Bi W, Xiong F, Wang R, Amirthalingam RT, Ren D, Han L, Jyothula SSSK, Li W, Zheng WJ, Karmouty-Quintana H. Hanmandlu A, et al. Among authors: mertens tcj. Am J Respir Cell Mol Biol. 2022 Jan;66(1):53-63. doi: 10.1165/rcmb.2020-0437OC. Am J Respir Cell Mol Biol. 2022. PMID: 34370624 Free PMC article.
Transforming growth factor β1 alters the 3'-UTR of mRNA to promote lung fibrosis.
Ko J, Mills T, Huang J, Chen NY, Mertens TCJ, Collum SD, Lee G, Xiang Y, Han L, Zhou Y, Lee CG, Elias JA, Jyothula SSK, Rajagopal K, Karmouty-Quintana H, Blackburn MR. Ko J, et al. Among authors: mertens tcj. J Biol Chem. 2019 Oct 25;294(43):15781-15794. doi: 10.1074/jbc.RA119.009148. Epub 2019 Sep 5. J Biol Chem. 2019. PMID: 31488543 Free PMC article.
Switching-Off Adora2b in Vascular Smooth Muscle Cells Halts the Development of Pulmonary Hypertension.
Mertens TCJ, Hanmandlu A, Tu L, Phan C, Collum SD, Chen NY, Weng T, Davies J, Liu C, Eltzschig HK, Jyothula SSK, Rajagopal K, Xia Y, Guha A, Bruckner BA, Blackburn MR, Guignabert C, Karmouty-Quintana H. Mertens TCJ, et al. Front Physiol. 2018 Jun 1;9:555. doi: 10.3389/fphys.2018.00555. eCollection 2018. Front Physiol. 2018. PMID: 29910735 Free PMC article.
Inhibition of hyaluronan synthesis attenuates pulmonary hypertension associated with lung fibrosis.
Collum SD, Chen NY, Hernandez AM, Hanmandlu A, Sweeney H, Mertens TCJ, Weng T, Luo F, Molina JG, Davies J, Horan IP, Morrell NW, Amione-Guerra J, Al-Jabbari O, Youker K, Sun W, Rajadas J, Bollyky PL, Akkanti BH, Jyothula S, Sinha N, Guha A, Karmouty-Quintana H. Collum SD, et al. Among authors: mertens tcj. Br J Pharmacol. 2017 Oct;174(19):3284-3301. doi: 10.1111/bph.13947. Epub 2017 Aug 17. Br J Pharmacol. 2017. PMID: 28688167 Free PMC article.
20 results