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Page 1
Regenerative Metaplastic Clones in COPD Lung Drive Inflammation and Fibrosis.
Rao W, Wang S, Duleba M, Niroula S, Goller K, Xie J, Mahalingam R, Neupane R, Liew AA, Vincent M, Okuda K, O'Neal WK, Boucher RC, Dickey BF, Wechsler ME, Ibrahim O, Engelhardt JF, Mertens TCJ, Wang W, Jyothula SSK, Crum CP, Karmouty-Quintana H, Parekh KR, Metersky ML, McKeon FD, Xian W. Rao W, et al. Among authors: mertens tcj. Cell. 2020 May 14;181(4):848-864.e18. doi: 10.1016/j.cell.2020.03.047. Epub 2020 Apr 15. Cell. 2020. PMID: 32298651 Free PMC article.
Inhibition of hyaluronan synthesis attenuates pulmonary hypertension associated with lung fibrosis.
Collum SD, Chen NY, Hernandez AM, Hanmandlu A, Sweeney H, Mertens TCJ, Weng T, Luo F, Molina JG, Davies J, Horan IP, Morrell NW, Amione-Guerra J, Al-Jabbari O, Youker K, Sun W, Rajadas J, Bollyky PL, Akkanti BH, Jyothula S, Sinha N, Guha A, Karmouty-Quintana H. Collum SD, et al. Among authors: mertens tcj. Br J Pharmacol. 2017 Oct;174(19):3284-3301. doi: 10.1111/bph.13947. Epub 2017 Aug 17. Br J Pharmacol. 2017. PMID: 28688167 Free PMC article.
Switching-Off Adora2b in Vascular Smooth Muscle Cells Halts the Development of Pulmonary Hypertension.
Mertens TCJ, Hanmandlu A, Tu L, Phan C, Collum SD, Chen NY, Weng T, Davies J, Liu C, Eltzschig HK, Jyothula SSK, Rajagopal K, Xia Y, Guha A, Bruckner BA, Blackburn MR, Guignabert C, Karmouty-Quintana H. Mertens TCJ, et al. Front Physiol. 2018 Jun 1;9:555. doi: 10.3389/fphys.2018.00555. eCollection 2018. Front Physiol. 2018. PMID: 29910735 Free PMC article.
Low-dose administration of bleomycin leads to early alterations in lung mechanics.
Headley L, Bi W, Wilson C, Collum SD, Chavez M, Darwiche T, Mertens TCJ, Hernandez AM, Siddiqui SR, Rosenbaum S, Johnston RA, Karmouty-Quintana H. Headley L, et al. Among authors: mertens tcj. Exp Physiol. 2018 Dec;103(12):1692-1703. doi: 10.1113/EP087322. Epub 2018 Oct 17. Exp Physiol. 2018. PMID: 30260066 Free article.
Cleavage factor 25 deregulation contributes to pulmonary fibrosis through alternative polyadenylation.
Weng T, Ko J, Masamha CP, Xia Z, Xiang Y, Chen NY, Molina JG, Collum S, Mertens TC, Luo F, Philip K, Davies J, Huang J, Wilson C, Thandavarayan RA, Bruckner BA, Jyothula SS, Volcik KA, Li L, Han L, Li W, Assassi S, Karmouty-Quintana H, Wagner EJ, Blackburn MR. Weng T, et al. J Clin Invest. 2019 Feb 28;129(5):1984-1999. doi: 10.1172/JCI122106. Print 2019 May 1. J Clin Invest. 2019. PMID: 30830875 Free PMC article.
Adenosine and hyaluronan promote lung fibrosis and pulmonary hypertension in combined pulmonary fibrosis and emphysema.
Collum SD, Molina JG, Hanmandlu A, Bi W, Pedroza M, Mertens TCJ, Wareing N, Wei W, Wilson C, Sun W, Rajadas J, Bollyky PL, Philip KM, Ren D, Thandavarayan RA, Bruckner BA, Xia Y, Blackburn MR, Karmouty-Quintana H. Collum SD, et al. Among authors: mertens tcj. Dis Model Mech. 2019 May 15;12(5):dmm038711. doi: 10.1242/dmm.038711. Dis Model Mech. 2019. PMID: 31036697 Free PMC article.
Transforming growth factor β1 alters the 3'-UTR of mRNA to promote lung fibrosis.
Ko J, Mills T, Huang J, Chen NY, Mertens TCJ, Collum SD, Lee G, Xiang Y, Han L, Zhou Y, Lee CG, Elias JA, Jyothula SSK, Rajagopal K, Karmouty-Quintana H, Blackburn MR. Ko J, et al. Among authors: mertens tcj. J Biol Chem. 2019 Oct 25;294(43):15781-15794. doi: 10.1074/jbc.RA119.009148. Epub 2019 Sep 5. J Biol Chem. 2019. PMID: 31488543 Free PMC article.
Versatile workflow for cell type-resolved transcriptional and epigenetic profiles from cryopreserved human lung.
Llamazares-Prada M, Espinet E, Mijošek V, Schwartz U, Lutsik P, Tamas R, Richter M, Behrendt A, Pohl ST, Benz NP, Muley T, Warth A, Heußel CP, Winter H, Landry JJM, Herth FJ, Mertens TC, Karmouty-Quintana H, Koch I, Benes V, Korbel JO, Waszak SM, Trumpp A, Wyatt DM, Stahl HF, Plass C, Jurkowska RZ. Llamazares-Prada M, et al. JCI Insight. 2021 Mar 22;6(6):e140443. doi: 10.1172/jci.insight.140443. JCI Insight. 2021. PMID: 33630765 Free PMC article.
20 results