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What the BTBR/J mouse has taught us about diabetes and diabetic complications.
Keller MP, Hudkins KL, Shalev A, Bhatnagar S, Kebede MA, Merrins MJ, Davis DB, Alpers CE, Kimple ME, Attie AD. Keller MP, et al. Among authors: merrins mj. iScience. 2023 Jun 7;26(7):107036. doi: 10.1016/j.isci.2023.107036. eCollection 2023 Jul 21. iScience. 2023. PMID: 37360692 Free PMC article. Review.
Decreased Consumption of Branched-Chain Amino Acids Improves Metabolic Health.
Fontana L, Cummings NE, Arriola Apelo SI, Neuman JC, Kasza I, Schmidt BA, Cava E, Spelta F, Tosti V, Syed FA, Baar EL, Veronese N, Cottrell SE, Fenske RJ, Bertozzi B, Brar HK, Pietka T, Bullock AD, Figenshau RS, Andriole GL, Merrins MJ, Alexander CM, Kimple ME, Lamming DW. Fontana L, et al. Among authors: merrins mj. Cell Rep. 2016 Jul 12;16(2):520-530. doi: 10.1016/j.celrep.2016.05.092. Epub 2016 Jun 23. Cell Rep. 2016. PMID: 27346343 Free PMC article. Clinical Trial.
Enriching Islet Phospholipids With Eicosapentaenoic Acid Reduces Prostaglandin E2 Signaling and Enhances Diabetic β-Cell Function.
Neuman JC, Schaid MD, Brill AL, Fenske RJ, Kibbe CR, Fontaine DA, Sdao SM, Brar HK, Connors KM, Wienkes HN, Eliceiri KW, Merrins MJ, Davis DB, Kimple ME. Neuman JC, et al. Among authors: merrins mj. Diabetes. 2017 Jun;66(6):1572-1585. doi: 10.2337/db16-1362. Epub 2017 Feb 13. Diabetes. 2017. PMID: 28193789 Free PMC article.
Radiomanganese PET Detects Changes in Functional β-Cell Mass in Mouse Models of Diabetes.
Hernandez R, Graves SA, Gregg T, VanDeusen HR, Fenske RJ, Wienkes HN, England CG, Valdovinos HF, Jeffery JJ, Barnhart TE, Severin GW, Nickles RJ, Kimple ME, Merrins MJ, Cai W. Hernandez R, et al. Among authors: merrins mj. Diabetes. 2017 Aug;66(8):2163-2174. doi: 10.2337/db16-1285. Epub 2017 May 17. Diabetes. 2017. PMID: 28515126 Free PMC article.
Restoration of metabolic health by decreased consumption of branched-chain amino acids.
Cummings NE, Williams EM, Kasza I, Konon EN, Schaid MD, Schmidt BA, Poudel C, Sherman DS, Yu D, Arriola Apelo SI, Cottrell SE, Geiger G, Barnes ME, Wisinski JA, Fenske RJ, Matkowskyj KA, Kimple ME, Alexander CM, Merrins MJ, Lamming DW. Cummings NE, et al. Among authors: merrins mj. J Physiol. 2018 Feb 15;596(4):623-645. doi: 10.1113/JP275075. Epub 2017 Dec 27. J Physiol. 2018. PMID: 29266268 Free PMC article.
Age-Dependent Protection of Insulin Secretion in Diet Induced Obese Mice.
De Leon ER, Brinkman JA, Fenske RJ, Gregg T, Schmidt BA, Sherman DS, Cummings NE, Peter DC, Kimple ME, Lamming DW, Merrins MJ. De Leon ER, et al. Among authors: merrins mj. Sci Rep. 2018 Dec 13;8(1):17814. doi: 10.1038/s41598-018-36289-0. Sci Rep. 2018. PMID: 30546031 Free PMC article.
Pyruvate Kinase Controls Signal Strength in the Insulin Secretory Pathway.
Lewandowski SL, Cardone RL, Foster HR, Ho T, Potapenko E, Poudel C, VanDeusen HR, Sdao SM, Alves TC, Zhao X, Capozzi ME, de Souza AH, Jahan I, Thomas CJ, Nunemaker CS, Davis DB, Campbell JE, Kibbey RG, Merrins MJ. Lewandowski SL, et al. Among authors: merrins mj. Cell Metab. 2020 Nov 3;32(5):736-750.e5. doi: 10.1016/j.cmet.2020.10.007. Cell Metab. 2020. PMID: 33147484 Free PMC article.
β Cell-specific deletion of Zfp148 improves nutrient-stimulated β cell Ca2+ responses.
Emfinger CH, de Klerk E, Schueler KL, Rabaglia ME, Stapleton DS, Simonett SP, Mitok KA, Wang Z, Liu X, Paulo JA, Yu Q, Cardone RL, Foster HR, Lewandowski SL, Perales JC, Kendziorski CM, Gygi SP, Kibbey RG, Keller MP, Hebrok M, Merrins MJ, Attie AD. Emfinger CH, et al. Among authors: merrins mj. JCI Insight. 2022 May 23;7(10):e154198. doi: 10.1172/jci.insight.154198. JCI Insight. 2022. PMID: 35603790 Free PMC article.
42 results