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Atractylenolide I enhances responsiveness to immune checkpoint blockade therapy by activating tumor antigen presentation.
Xu H, Van der Jeught K, Zhou Z, Zhang L, Yu T, Sun Y, Li Y, Wan C, So KM, Liu D, Frieden M, Fang Y, Mosley AL, He X, Zhang X, Sandusky GE, Liu Y, Meroueh SO, Zhang C, Wijeratne AB, Huang C, Ji G, Lu X. Xu H, et al. Among authors: meroueh so. J Clin Invest. 2021 May 17;131(10):e146832. doi: 10.1172/JCI146832. J Clin Invest. 2021. PMID: 33830945 Free PMC article.
Virtual screening targeting the urokinase receptor, biochemical and cell-based studies, synthesis, pharmacokinetic characterization, and effect on breast tumor metastasis.
Wang F, Li J, Sinn AL, Knabe WE, Khanna M, Jo I, Silver JM, Oh K, Li L, Sandusky GE, Sledge GW, Nakshatri H, Jones DR, Pollok KE, Meroueh SO. Wang F, et al. Among authors: meroueh so. J Med Chem. 2011 Oct 27;54(20):7193-205. doi: 10.1021/jm200782y. Epub 2011 Oct 4. J Med Chem. 2011. PMID: 21851064 Free PMC article.
Small-molecule inhibition of the uPAR·uPA interaction: synthesis, biochemical, cellular, in vivo pharmacokinetics and efficacy studies in breast cancer metastasis.
Mani T, Wang F, Knabe WE, Sinn AL, Khanna M, Jo I, Sandusky GE, Sledge GW Jr, Jones DR, Khanna R, Pollok KE, Meroueh SO. Mani T, et al. Among authors: meroueh so. Bioorg Med Chem. 2013 Apr 1;21(7):2145-55. doi: 10.1016/j.bmc.2012.12.047. Epub 2013 Jan 9. Bioorg Med Chem. 2013. PMID: 23411397 Free PMC article.
Small molecules inhibit ex vivo tumor growth in bone.
Zhou D, Bum-Erdene K, Xu D, Liu D, Tompkins D, Sulaiman RS, Corson TW, Chirgwin JM, Meroueh SO. Zhou D, et al. Among authors: meroueh so. Bioorg Med Chem. 2018 Dec 15;26(23-24):6128-6134. doi: 10.1016/j.bmc.2018.11.025. Epub 2018 Nov 16. Bioorg Med Chem. 2018. PMID: 30470597 Free article.
80 results