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Alzheimer's disease: brain expression of a metabolic disorder?
Merlo S, Spampinato S, Canonico PL, Copani A, Sortino MA. Merlo S, et al. Trends Endocrinol Metab. 2010 Sep;21(9):537-44. doi: 10.1016/j.tem.2010.05.005. Epub 2010 Jun 11. Trends Endocrinol Metab. 2010. PMID: 20541952 Review.
Targeting group II metabotropic glutamate (mGlu) receptors for the treatment of psychosis associated with Alzheimer's disease: selective activation of mGlu2 receptors amplifies beta-amyloid toxicity in cultured neurons, whereas dual activation of mGlu2 and mGlu3 receptors is neuroprotective.
Caraci F, Molinaro G, Battaglia G, Giuffrida ML, Riozzi B, Traficante A, Bruno V, Cannella M, Merlo S, Wang X, Heinz BA, Nisenbaum ES, Britton TC, Drago F, Sortino MA, Copani A, Nicoletti F. Caraci F, et al. Among authors: merlo s. Mol Pharmacol. 2011 Mar;79(3):618-26. doi: 10.1124/mol.110.067488. Epub 2010 Dec 15. Mol Pharmacol. 2011. PMID: 21159998
116 results