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New insights into the regulation of bile acids synthesis during the early stages of liver regeneration: A human and experimental study.
Uriarte I, Santamaria E, López-Pascual A, Monte MJ, Argemí J, Latasa MU, Adán-Villaescusa E, Irigaray A, Herranz JM, Arechederra M, Basualdo J, Lucena F, Corrales FJ, Rotellar F, Pardo F, Merlen G, Rainteau D, Sangro B, Tordjmann T, Berasain C, Marín JJG, Fernández-Barrena MG, Herrero I, Avila MA. Uriarte I, et al. Among authors: merlen g. Biochim Biophys Acta Mol Basis Dis. 2024 Apr 19;1870(5):167166. doi: 10.1016/j.bbadis.2024.167166. Online ahead of print. Biochim Biophys Acta Mol Basis Dis. 2024. PMID: 38642480 Free article.
Tight junction proteins and biliary diseases.
Merlen G, Tordjmann T. Merlen G, et al. Curr Opin Gastroenterol. 2024 Mar 1;40(2):70-76. doi: 10.1097/MOG.0000000000000996. Epub 2024 Jan 19. Curr Opin Gastroenterol. 2024. PMID: 38260939 Review.
Hepatic deletion of serine palmitoyl transferase 2 impairs ceramide/sphingomyelin balance, bile acids homeostasis and leads to liver damage in mice.
Lallement J, Raho I, Merlen G, Rainteau D, Croyal M, Schiffano M, Kassis N, Doignon I, Soty M, Lachkar F, Krempf M, Van Hul M, Cani PD, Foufelle F, Amouyal C, Le Stunff H, Magnan C, Tordjmann T, Cruciani-Guglielmacci C. Lallement J, et al. Among authors: merlen g. Biochim Biophys Acta Mol Cell Biol Lipids. 2023 Aug;1868(8):159333. doi: 10.1016/j.bbalip.2023.159333. Epub 2023 May 22. Biochim Biophys Acta Mol Cell Biol Lipids. 2023. PMID: 37224999 Free article.
Bile acid-receptor TGR5 deficiency worsens liver injury in alcohol-fed mice by inducing intestinal microbiota dysbiosis.
Spatz M, Ciocan D, Merlen G, Rainteau D, Humbert L, Gomes-Rochette N, Hugot C, Trainel N, Mercier-Nomé F, Domenichini S, Puchois V, Wrzosek L, Ferrere G, Tordjmann T, Perlemuter G, Cassard AM. Spatz M, et al. Among authors: merlen g. JHEP Rep. 2021 Jan 19;3(2):100230. doi: 10.1016/j.jhepr.2021.100230. eCollection 2021 Apr. JHEP Rep. 2021. PMID: 33665587 Free PMC article.
TGR5 controls bile acid composition and gallbladder function to protect the liver from bile acid overload.
Bidault-Jourdainne V, Merlen G, Glénisson M, Doignon I, Garcin I, Péan N, Boisgard R, Ursic-Bedoya J, Serino M, Ullmer C, Humbert L, Abdelrafee A, Golse N, Vibert E, Duclos-Vallée JC, Rainteau D, Tordjmann T. Bidault-Jourdainne V, et al. Among authors: merlen g. JHEP Rep. 2020 Nov 11;3(2):100214. doi: 10.1016/j.jhepr.2020.100214. eCollection 2021 Apr. JHEP Rep. 2020. PMID: 33604531 Free PMC article.
[The EGFR ligand amphiregulin protects from cholestatic liver injury].
Sidibé N, Jalabert H, Merlen G, Tordjmann T. Sidibé N, et al. Among authors: merlen g. Med Sci (Paris). 2021 Jan;37(1):103-105. doi: 10.1051/medsci/2020265. Epub 2021 Jan 25. Med Sci (Paris). 2021. PMID: 33492227 Free article. French. No abstract available.
Hepatoprotective impact of the bile acid receptor TGR5.
Merlen G, Bidault-Jourdainne V, Kahale N, Glenisson M, Ursic-Bedoya J, Doignon I, Garcin I, Humbert L, Rainteau D, Tordjmann T. Merlen G, et al. Liver Int. 2020 May;40(5):1005-1015. doi: 10.1111/liv.14427. Epub 2020 Mar 30. Liver Int. 2020. PMID: 32145703
20 results