Merkel AR - Search Results

1

Systemic delivery of a Gli inhibitor via polymeric nanocarriers inhibits tumor-induced bone disease.

Vanderburgh JP, Kwakwa KA, Werfel TA, Merkel AR, Gupta MK, Johnson RW, Guelcher SA, Duvall CL, Rhoades JA. Vanderburgh JP, et al. Among authors: merkel ar. J Control Release. 2019 Oct;311-312:257-272. doi: 10.1016/j.jconrel.2019.08.038. Epub 2019 Sep 5. J Control Release. 2019. PMID: 31494183 Free PMC article.

2

Matrix rigidity induces osteolytic gene expression of metastatic breast cancer cells.

Ruppender NS, Merkel AR, Martin TJ, Mundy GR, Sterling JA, Guelcher SA. Ruppender NS, et al. Among authors: merkel ar. PLoS One. 2010 Nov 15;5(11):e15451. doi: 10.1371/journal.pone.0015451. PLoS One. 2010. PMID: 21085597 Free PMC article.

3

TGF-beta promotion of Gli2-induced expression of parathyroid hormone-related protein, an important osteolytic factor in bone metastasis, is independent of canonical Hedgehog signaling.

Johnson RW, Nguyen MP, Padalecki SS, Grubbs BG, Merkel AR, Oyajobi BO, Matrisian LM, Mundy GR, Sterling JA. Johnson RW, et al. Among authors: merkel ar. Cancer Res. 2011 Feb 1;71(3):822-31. doi: 10.1158/0008-5472.CAN-10-2993. Epub 2010 Dec 28. Cancer Res. 2011. PMID: 21189326 Free PMC article.

4

6-Thioguanine inhibition of parathyroid hormone-related protein expression is mediated by GLI2.

Johnson RW, Merkel AR, Danilin S, Nguyen MP, Mundy GR, Sterling JA. Johnson RW, et al. Among authors: merkel ar. Anticancer Res. 2011 Sep;31(9):2705-12. Anticancer Res. 2011. PMID: 21868511 Free PMC article.

5

Models of bone metastasis.

Campbell JP, Merkel AR, Masood-Campbell SK, Elefteriou F, Sterling JA. Campbell JP, et al. Among authors: merkel ar. J Vis Exp. 2012 Sep 4;(67):e4260. doi: 10.3791/4260. J Vis Exp. 2012. PMID: 22972196 Free PMC article.

6

Myeloid-derived suppressor cells expand during breast cancer progression and promote tumor-induced bone destruction.

Danilin S, Merkel AR, Johnson JR, Johnson RW, Edwards JR, Sterling JA. Danilin S, et al. Among authors: merkel ar. Oncoimmunology. 2012 Dec 1;1(9):1484-1494. doi: 10.4161/onci.21990. Oncoimmunology. 2012. PMID: 23264895 Free PMC article.

7

Wnt signaling induces gene expression of factors associated with bone destruction in lung and breast cancer.

Johnson RW, Merkel AR, Page JM, Ruppender NS, Guelcher SA, Sterling JA. Johnson RW, et al. Among authors: merkel ar. Clin Exp Metastasis. 2014 Dec;31(8):945-59. doi: 10.1007/s10585-014-9682-1. Epub 2014 Oct 31. Clin Exp Metastasis. 2014. PMID: 25359619 Free PMC article.

8

Matrix rigidity regulates the transition of tumor cells to a bone-destructive phenotype through integrin β3 and TGF-β receptor type II.

Page JM, Merkel AR, Ruppender NS, Guo R, Dadwal UC, Cannonier S, Basu S, Guelcher SA, Sterling JA. Page JM, et al. Among authors: merkel ar. Biomaterials. 2015 Sep;64:33-44. doi: 10.1016/j.biomaterials.2015.06.026. Epub 2015 Jun 16. Biomaterials. 2015. PMID: 26115412 Free PMC article.

9

Fabrication of 3D Scaffolds with Precisely Controlled Substrate Modulus and Pore Size by Templated-Fused Deposition Modeling to Direct Osteogenic Differentiation.

Guo R, Lu S, Page JM, Merkel AR, Basu S, Sterling JA, Guelcher SA. Guo R, et al. Among authors: merkel ar. Adv Healthc Mater. 2015 Aug 26;4(12):1826-32. doi: 10.1002/adhm.201500099. Epub 2015 Jun 29. Adv Healthc Mater. 2015. PMID: 26121662 Free PMC article.

10

Altering adsorbed proteins or cellular gene expression in bone-metastatic cancer cells affects PTHrP and Gli2 without altering cell growth.

Page JM, Merkel AR, Ruppender NS, Guo R, Dadwal UC, Cannonier S, Basu S, Guelcher SA, Sterling JA. Page JM, et al. Among authors: merkel ar. Data Brief. 2015 Jul 13;4:440-6. doi: 10.1016/j.dib.2015.07.003. eCollection 2015 Sep. Data Brief. 2015. PMID: 26306316 Free PMC article.

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