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An Fc-free EGFR-specific 4-1BB-agonistic Trimerbody Displays Broad Antitumor Activity in Humanized Murine Cancer Models without Toxicity.
Compte M, Harwood SL, Erce-Llamazares A, Tapia-Galisteo A, Romero E, Ferrer I, Garrido-Martin EM, Enguita AB, Ochoa MC, Blanco B, Oteo M, Merino N, Nehme-Álvarez D, Hangiu O, Domínguez-Alonso C, Zonca M, Ramírez-Fernández A, Blanco FJ, Morcillo MA, Muñoz IG, Melero I, Rodriguez-Peralto JL, Paz-Ares L, Sanz L, Alvarez-Vallina L. Compte M, et al. Among authors: merino n. Clin Cancer Res. 2021 Jun 1;27(11):3167-3177. doi: 10.1158/1078-0432.CCR-20-4625. Epub 2021 Mar 30. Clin Cancer Res. 2021. PMID: 33785484
Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus.
Muñoz IG, Prieto J, Subramanian S, Coloma J, Redondo P, Villate M, Merino N, Marenchino M, D'Abramo M, Gervasio FL, Grizot S, Daboussi F, Smith J, Chion-Sotinel I, Pâques F, Duchateau P, Alibés A, Stricher F, Serrano L, Blanco FJ, Montoya G. Muñoz IG, et al. Among authors: merino n. Nucleic Acids Res. 2011 Jan;39(2):729-43. doi: 10.1093/nar/gkq801. Epub 2010 Sep 16. Nucleic Acids Res. 2011. PMID: 20846960 Free PMC article.
Proliferating cell nuclear antigen (PCNA) interactions in solution studied by NMR.
De Biasio A, Campos-Olivas R, Sánchez R, López-Alonso JP, Pantoja-Uceda D, Merino N, Villate M, Martin-Garcia JM, Castillo F, Luque I, Blanco FJ. De Biasio A, et al. Among authors: merino n. PLoS One. 2012;7(11):e48390. doi: 10.1371/journal.pone.0048390. Epub 2012 Nov 6. PLoS One. 2012. PMID: 23139781 Free PMC article.
Generation and characterization of monospecific and bispecific hexavalent trimerbodies.
Blanco-Toribio A, Sainz-Pastor N, Álvarez-Cienfuegos A, Merino N, Cuesta ÁM, Sánchez-Martín D, Bonet J, Santos-Valle P, Sanz L, Oliva B, Blanco FJ, Álvarez-Vallina L. Blanco-Toribio A, et al. Among authors: merino n. MAbs. 2013 Jan-Feb;5(1):70-9. doi: 10.4161/mabs.22698. Epub 2012 Dec 5. MAbs. 2013. PMID: 23221741 Free PMC article.
Intramolecular trimerization, a novel strategy for making multispecific antibodies with controlled orientation of the antigen binding domains.
Alvarez-Cienfuegos A, Nuñez-Prado N, Compte M, Cuesta AM, Blanco-Toribio A, Harwood SL, Villate M, Merino N, Bonet J, Navarro R, Muñoz-Briones C, Sørensen KM, Mølgaard K, Oliva B, Sanz L, Blanco FJ, Alvarez-Vallina L. Alvarez-Cienfuegos A, et al. Among authors: merino n. Sci Rep. 2016 Jun 27;6:28643. doi: 10.1038/srep28643. Sci Rep. 2016. PMID: 27345490 Free PMC article.
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