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Metabolic Maturation Media Improve Physiological Function of Human iPSC-Derived Cardiomyocytes.
Feyen DAM, McKeithan WL, Bruyneel AAN, Spiering S, Hörmann L, Ulmer B, Zhang H, Briganti F, Schweizer M, Hegyi B, Liao Z, Pölönen RP, Ginsburg KS, Lam CK, Serrano R, Wahlquist C, Kreymerman A, Vu M, Amatya PL, Behrens CS, Ranjbarvaziri S, Maas RGC, Greenhaw M, Bernstein D, Wu JC, Bers DM, Eschenhagen T, Metallo CM, Mercola M. Feyen DAM, et al. Among authors: mercola m. Cell Rep. 2020 Jul 21;32(3):107925. doi: 10.1016/j.celrep.2020.107925. Cell Rep. 2020. PMID: 32697997 Free PMC article.
Human iPSC modeling of heart disease for drug development.
Hnatiuk AP, Briganti F, Staudt DW, Mercola M. Hnatiuk AP, et al. Among authors: mercola m. Cell Chem Biol. 2021 Mar 18;28(3):271-282. doi: 10.1016/j.chembiol.2021.02.016. Cell Chem Biol. 2021. PMID: 33740432 Free PMC article. Review.
miR-132/212 Impairs Cardiomyocytes Contractility in the Failing Heart by Suppressing SERCA2a.
Lei Z, Wahlquist C, El Azzouzi H, Deddens JC, Kuster D, van Mil A, Rojas-Munoz A, Huibers MM, Mercola M, de Weger R, Van der Velden J, Xiao J, Doevendans PA, Sluijter JPG. Lei Z, et al. Among authors: mercola m. Front Cardiovasc Med. 2021 Mar 19;8:592362. doi: 10.3389/fcvm.2021.592362. eCollection 2021. Front Cardiovasc Med. 2021. PMID: 33816571 Free PMC article.
CRISPR/Cas9-based targeting of fluorescent reporters to human iPSCs to isolate atrial and ventricular-specific cardiomyocytes.
Chirikian O, Goodyer WR, Dzilic E, Serpooshan V, Buikema JW, McKeithan W, Wu H, Li G, Lee S, Merk M, Galdos F, Beck A, Ribeiro AJS, Paige S, Mercola M, Wu JC, Pruitt BL, Wu SM. Chirikian O, et al. Among authors: mercola m. Sci Rep. 2021 Feb 4;11(1):3026. doi: 10.1038/s41598-021-81860-x. Sci Rep. 2021. PMID: 33542270 Free PMC article.
Unfolded Protein Response as a Compensatory Mechanism and Potential Therapeutic Target in PLN R14del Cardiomyopathy.
Feyen DAM, Perea-Gil I, Maas RGC, Harakalova M, Gavidia AA, Arthur Ataam J, Wu TH, Vink A, Pei J, Vadgama N, Suurmeijer AJ, Te Rijdt WP, Vu M, Amatya PL, Prado M, Zhang Y, Dunkenberger L, Sluijter JPG, Sallam K, Asselbergs FW, Mercola M, Karakikes I. Feyen DAM, et al. Among authors: mercola m. Circulation. 2021 Aug 3;144(5):382-392. doi: 10.1161/CIRCULATIONAHA.120.049844. Epub 2021 Apr 30. Circulation. 2021. PMID: 33928785 Free PMC article.
Inhibition of miR-25 improves cardiac contractility in the failing heart.
Wahlquist C, Jeong D, Rojas-Muñoz A, Kho C, Lee A, Mitsuyama S, van Mil A, Park WJ, Sluijter JP, Doevendans PA, Hajjar RJ, Mercola M. Wahlquist C, et al. Among authors: mercola m. Nature. 2014 Apr 24;508(7497):531-5. doi: 10.1038/nature13073. Epub 2014 Mar 12. Nature. 2014. PMID: 24670661 Free PMC article.
173 results