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Assessment of a white matter reference region for 11C-UCB-J PET quantification.
Rossano S, Toyonaga T, Finnema SJ, Naganawa M, Lu Y, Nabulsi N, Ropchan J, De Bruyn S, Otoul C, Stockis A, Nicolas JM, Martin P, Mercier J, Huang Y, Maguire RP, Carson RE. Rossano S, et al. Among authors: mercier j. J Cereb Blood Flow Metab. 2020 Sep;40(9):1890-1901. doi: 10.1177/0271678X19879230. Epub 2019 Sep 30. J Cereb Blood Flow Metab. 2020. PMID: 31570041 Free PMC article.
Evaluation of 18F-UCB-H as a novel PET tracer for synaptic vesicle protein 2A in the brain.
Warnock GI, Aerts J, Bahri MA, Bretin F, Lemaire C, Giacomelli F, Mievis F, Mestdagh N, Buchanan T, Valade A, Mercier J, Wood M, Gillard M, Seret A, Luxen A, Salmon E, Plenevaux A. Warnock GI, et al. Among authors: mercier j. J Nucl Med. 2014 Aug;55(8):1336-41. doi: 10.2967/jnumed.113.136143. Epub 2014 Jun 16. J Nucl Med. 2014. PMID: 24935992 Free article.
Brivaracetam, a selective high-affinity synaptic vesicle protein 2A (SV2A) ligand with preclinical evidence of high brain permeability and fast onset of action.
Nicolas JM, Hannestad J, Holden D, Kervyn S, Nabulsi N, Tytgat D, Huang Y, Chanteux H, Staelens L, Matagne A, Mathy FX, Mercier J, Stockis A, Carson RE, Klitgaard H. Nicolas JM, et al. Among authors: mercier j. Epilepsia. 2016 Feb;57(2):201-9. doi: 10.1111/epi.13267. Epub 2015 Dec 10. Epilepsia. 2016. PMID: 26663401 Free article.
Synthesis and Preclinical Evaluation of 11C-UCB-J as a PET Tracer for Imaging the Synaptic Vesicle Glycoprotein 2A in the Brain.
Nabulsi NB, Mercier J, Holden D, Carré S, Najafzadeh S, Vandergeten MC, Lin SF, Deo A, Price N, Wood M, Lara-Jaime T, Montel F, Laruelle M, Carson RE, Hannestad J, Huang Y. Nabulsi NB, et al. Among authors: mercier j. J Nucl Med. 2016 May;57(5):777-84. doi: 10.2967/jnumed.115.168179. Epub 2016 Feb 4. J Nucl Med. 2016. PMID: 26848175 Free article.
[(11)C]UCB-A, a novel PET tracer for synaptic vesicle protein 2A.
Estrada S, Lubberink M, Thibblin A, Sprycha M, Buchanan T, Mestdagh N, Kenda B, Mercier J, Provins L, Gillard M, Tytgat D, Antoni G. Estrada S, et al. Among authors: mercier j. Nucl Med Biol. 2016 Jun;43(6):325-32. doi: 10.1016/j.nucmedbio.2016.03.004. Epub 2016 Mar 17. Nucl Med Biol. 2016. PMID: 27260773
Imaging synaptic density in the living human brain.
Finnema SJ, Nabulsi NB, Eid T, Detyniecki K, Lin SF, Chen MK, Dhaher R, Matuskey D, Baum E, Holden D, Spencer DD, Mercier J, Hannestad J, Huang Y, Carson RE. Finnema SJ, et al. Among authors: mercier j. Sci Transl Med. 2016 Jul 20;8(348):348ra96. doi: 10.1126/scitranslmed.aaf6667. Sci Transl Med. 2016. PMID: 27440727 Clinical Trial.
Enabling Efficient Positron Emission Tomography (PET) Imaging of Synaptic Vesicle Glycoprotein 2A (SV2A) with a Robust and One-Step Radiosynthesis of a Highly Potent 18F-Labeled Ligand ([18F]UCB-H).
Warnier C, Lemaire C, Becker G, Zaragoza G, Giacomelli F, Aerts J, Otabashi M, Bahri MA, Mercier J, Plenevaux A, Luxen A. Warnier C, et al. Among authors: mercier j. J Med Chem. 2016 Oct 13;59(19):8955-8966. doi: 10.1021/acs.jmedchem.6b00905. Epub 2016 Sep 20. J Med Chem. 2016. PMID: 27598384
Kinetic evaluation and test-retest reproducibility of [11C]UCB-J, a novel radioligand for positron emission tomography imaging of synaptic vesicle glycoprotein 2A in humans.
Finnema SJ, Nabulsi NB, Mercier J, Lin SF, Chen MK, Matuskey D, Gallezot JD, Henry S, Hannestad J, Huang Y, Carson RE. Finnema SJ, et al. Among authors: mercier j. J Cereb Blood Flow Metab. 2018 Nov;38(11):2041-2052. doi: 10.1177/0271678X17724947. Epub 2017 Aug 9. J Cereb Blood Flow Metab. 2018. PMID: 28792356 Free PMC article.
1,117 results