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A general copper-mediated nucleophilic 18F fluorination of arenes.
Tredwell M, Preshlock SM, Taylor NJ, Gruber S, Huiban M, Passchier J, Mercier J, Génicot C, Gouverneur V. Tredwell M, et al. Among authors: mercier j. Angew Chem Int Ed Engl. 2014 Jul 21;53(30):7751-5. doi: 10.1002/anie.201404436. Epub 2014 Jun 10. Angew Chem Int Ed Engl. 2014. PMID: 24916101
Enhanced copper-mediated (18)F-fluorination of aryl boronic esters provides eight radiotracers for PET applications.
Preshlock S, Calderwood S, Verhoog S, Tredwell M, Huiban M, Hienzsch A, Gruber S, Wilson TC, Taylor NJ, Cailly T, Schedler M, Collier TL, Passchier J, Smits R, Mollitor J, Hoepping A, Mueller M, Genicot C, Mercier J, Gouverneur V. Preshlock S, et al. Among authors: mercier j. Chem Commun (Camb). 2016 Jun 28;52(54):8361-4. doi: 10.1039/c6cc03295h. Chem Commun (Camb). 2016. PMID: 27241832
Bridging the gaps in 18F PET tracer development.
Campbell MG, Mercier J, Genicot C, Gouverneur V, Hooker JM, Ritter T. Campbell MG, et al. Among authors: mercier j. Nat Chem. 2016 Dec 20;9(1):1-3. doi: 10.1038/nchem.2693. Nat Chem. 2016. PMID: 27995923 No abstract available.
Evaluation and Application of a PET Tracer in Preclinical and Phase 1 Studies to Determine the Brain Biodistribution of Minzasolmin (UCB0599).
Mercier J, Bani M, Colson AO, Germani M, Lalla M, Plisson C, Huiban M, Searle G, Mathy FX, Nicholl R, Otoul C, Smit JW, van Asch V, Wagneur M, Maguire RP. Mercier J, et al. Mol Imaging Biol. 2024 Apr;26(2):310-321. doi: 10.1007/s11307-023-01878-7. Epub 2023 Dec 18. Mol Imaging Biol. 2024. PMID: 38110790 Free PMC article. Clinical Trial.
Discovery of heterocyclic nonacetamide synaptic vesicle protein 2A (SV2A) ligands with single-digit nanomolar potency: opening avenues towards the first SV2A positron emission tomography (PET) ligands.
Mercier J, Archen L, Bollu V, Carré S, Evrard Y, Jnoff E, Kenda B, Lallemand B, Michel P, Montel F, Moureau F, Price N, Quesnel Y, Sauvage X, Valade A, Provins L. Mercier J, et al. ChemMedChem. 2014 Apr;9(4):693-8. doi: 10.1002/cmdc.201300482. Epub 2014 Jan 20. ChemMedChem. 2014. PMID: 24446373
1,117 results