Mercer KL - Search Results

1

Keap1 mutation renders lung adenocarcinomas dependent on Slc33a1.

Romero R, Sánchez-Rivera FJ, Westcott PMK, Mercer KL, Bhutkar A, Muir A, González Robles TJ, Lamboy Rodríguez S, Liao LZ, Ng SR, Li L, Colón CI, Naranjo S, Beytagh MC, Lewis CA, Hsu PP, Bronson RT, Vander Heiden MG, Jacks T. Romero R, et al. Among authors: mercer kl. Nat Cancer. 2020 Jun;1(6):589-602. doi: 10.1038/s43018-020-0071-1. Epub 2020 Jun 8. Nat Cancer. 2020. PMID: 34414377 Free PMC article.

2

K-ras is an essential gene in the mouse with partial functional overlap with N-ras.

Johnson L, Greenbaum D, Cichowski K, Mercer K, Murphy E, Schmitt E, Bronson RT, Umanoff H, Edelmann W, Kucherlapati R, Jacks T. Johnson L, et al. Genes Dev. 1997 Oct 1;11(19):2468-81. doi: 10.1101/gad.11.19.2468. Genes Dev. 1997. PMID: 9334313 Free PMC article.

3

Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors.

McClatchey AI, Saotome I, Mercer K, Crowley D, Gusella JF, Bronson RT, Jacks T. McClatchey AI, et al. Genes Dev. 1998 Apr 15;12(8):1121-33. doi: 10.1101/gad.12.8.1121. Genes Dev. 1998. PMID: 9553042 Free PMC article.

4

Somatic activation of the K-ras oncogene causes early onset lung cancer in mice.

Johnson L, Mercer K, Greenbaum D, Bronson RT, Crowley D, Tuveson DA, Jacks T. Johnson L, et al. Nature. 2001 Apr 26;410(6832):1111-6. doi: 10.1038/35074129. Nature. 2001. PMID: 11323676

5

Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras.

Jackson EL, Willis N, Mercer K, Bronson RT, Crowley D, Montoya R, Jacks T, Tuveson DA. Jackson EL, et al. Genes Dev. 2001 Dec 15;15(24):3243-8. doi: 10.1101/gad.943001. Genes Dev. 2001. PMID: 11751630 Free PMC article.

6

ARF mutation accelerates pituitary tumor development in Rb+/- mice.

Tsai KY, MacPherson D, Rubinson DA, Nikitin AY, Bronson R, Mercer KL, Crowley D, Jacks T. Tsai KY, et al. Among authors: mercer kl. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16865-70. doi: 10.1073/pnas.262499599. Epub 2002 Dec 16. Proc Natl Acad Sci U S A. 2002. PMID: 12486224 Free PMC article.

7

Targeted deletion reveals an essential function for the telomere length regulator Trf1.

Karlseder J, Kachatrian L, Takai H, Mercer K, Hingorani S, Jacks T, de Lange T. Karlseder J, et al. Mol Cell Biol. 2003 Sep;23(18):6533-41. doi: 10.1128/MCB.23.18.6533-6541.2003. Mol Cell Biol. 2003. PMID: 12944479 Free PMC article.

8

Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects.

Tuveson DA, Shaw AT, Willis NA, Silver DP, Jackson EL, Chang S, Mercer KL, Grochow R, Hock H, Crowley D, Hingorani SR, Zaks T, King C, Jacobetz MA, Wang L, Bronson RT, Orkin SH, DePinho RA, Jacks T. Tuveson DA, et al. Among authors: mercer kl. Cancer Cell. 2004 Apr;5(4):375-87. doi: 10.1016/s1535-6108(04)00085-6. Cancer Cell. 2004. PMID: 15093544 Free article.

9

Impaired microRNA processing enhances cellular transformation and tumorigenesis.

Kumar MS, Lu J, Mercer KL, Golub TR, Jacks T. Kumar MS, et al. Among authors: mercer kl. Nat Genet. 2007 May;39(5):673-7. doi: 10.1038/ng2003. Epub 2007 Apr 1. Nat Genet. 2007. PMID: 17401365

10

Modulation of tumor induction and progression of oncogenic K-ras-positive tumors in the presence of TGF- b1 haploinsufficiency.

Pandey J, Umphress SM, Kang Y, Angdisen J, Naumova A, Mercer KL, Jacks T, Jakowlew SB. Pandey J, et al. Among authors: mercer kl. Carcinogenesis. 2007 Dec;28(12):2589-96. doi: 10.1093/carcin/bgm136. Epub 2007 Aug 8. Carcinogenesis. 2007. PMID: 17690114

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