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Gluten-induced RNA methylation changes regulate intestinal inflammation via allele-specific XPO1 translation in epithelial cells.
Olazagoitia-Garmendia A, Zhang L, Mera P, Godbout JK, Sebastian-DelaCruz M, Garcia-Santisteban I, Mendoza LM, Huerta A, Irastorza I, Bhagat G, Green PH, Herrero L, Serra D, Rodriguez JA, Verdu EF, He C, Bilbao JR, Castellanos-Rubio A. Olazagoitia-Garmendia A, et al. Among authors: mera p. Gut. 2022 Jan;71(1):68-76. doi: 10.1136/gutjnl-2020-322566. Epub 2021 Feb 1. Gut. 2022. PMID: 33526437 Free PMC article.
C75 is converted to C75-CoA in the hypothalamus, where it inhibits carnitine palmitoyltransferase 1 and decreases food intake and body weight.
Mera P, Bentebibel A, López-Viñas E, Cordente AG, Gurunathan C, Sebastián D, Vázquez I, Herrero L, Ariza X, Gómez-Puertas P, Asins G, Serra D, García J, Hegardt FG. Mera P, et al. Biochem Pharmacol. 2009 Mar 15;77(6):1084-95. doi: 10.1016/j.bcp.2008.11.020. Epub 2008 Nov 27. Biochem Pharmacol. 2009. PMID: 19094968
Mitochondrial fatty acid oxidation in obesity.
Serra D, Mera P, Malandrino MI, Mir JF, Herrero L. Serra D, et al. Among authors: mera p. Antioxid Redox Signal. 2013 Jul 20;19(3):269-84. doi: 10.1089/ars.2012.4875. Epub 2012 Oct 5. Antioxid Redox Signal. 2013. PMID: 22900819 Free PMC article. Review.
Long-term increased carnitine palmitoyltransferase 1A expression in ventromedial hypotalamus causes hyperphagia and alters the hypothalamic lipidomic profile.
Mera P, Mir JF, Fabriàs G, Casas J, Costa AS, Malandrino MI, Fernández-López JA, Remesar X, Gao S, Chohnan S, Rodríguez-Peña MS, Petry H, Asins G, Hegardt FG, Herrero L, Serra D. Mera P, et al. PLoS One. 2014 May 12;9(5):e97195. doi: 10.1371/journal.pone.0097195. eCollection 2014. PLoS One. 2014. PMID: 24819600 Free PMC article.
The role of epigenetics in the development of obesity.
Obri A, Serra D, Herrero L, Mera P. Obri A, et al. Among authors: mera p. Biochem Pharmacol. 2020 Jul;177:113973. doi: 10.1016/j.bcp.2020.113973. Epub 2020 Apr 10. Biochem Pharmacol. 2020. PMID: 32283053 Review.
61 results