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IPO11 regulates the nuclear import of BZW1/2 and is necessary for AML cells and stem cells.
Nachmias B, Khan DH, Voisin V, Mer AS, Thomas GE, Segev N, St-Germain J, Hurren R, Gronda M, Botham A, Wang X, Maclean N, Seneviratne AK, Duong N, Xu C, Arruda A, Orouji E, Algouneh A, Hakem R, Shlush L, Minden MD, Raught B, Bader GD, Schimmer AD. Nachmias B, et al. Among authors: mer as. Leukemia. 2022 May;36(5):1283-1295. doi: 10.1038/s41375-022-01513-4. Epub 2022 Feb 12. Leukemia. 2022. PMID: 35152270 Free PMC article.
Biological and therapeutic implications of a unique subtype of NPM1 mutated AML.
Mer AS, Heath EM, Madani Tonekaboni SA, Dogan-Artun N, Nair SK, Murison A, Garcia-Prat L, Shlush L, Hurren R, Voisin V, Bader GD, Nislow C, Rantalainen M, Lehmann S, Gower M, Guidos CJ, Lupien M, Dick JE, Minden MD, Schimmer AD, Haibe-Kains B. Mer AS, et al. Nat Commun. 2021 Feb 16;12(1):1054. doi: 10.1038/s41467-021-21233-0. Nat Commun. 2021. PMID: 33594052 Free PMC article.
Novel subtypes of NPM1-mutated AML with distinct outcome.
Mer AS, Minden MD, Haibe-Kains B, Schimmer AD. Mer AS, et al. Mol Cell Oncol. 2021 Jun 30;8(4):1924600. doi: 10.1080/23723556.2021.1924600. eCollection 2021. Mol Cell Oncol. 2021. PMID: 34616866 Free PMC article.
Orchestrating and sharing large multimodal data for transparent and reproducible research.
Mammoliti A, Smirnov P, Nakano M, Safikhani Z, Eeles C, Seo H, Nair SK, Mer AS, Smith I, Ho C, Beri G, Kusko R; Massive Analysis Quality Control (MAQC) Society Board of Directors; Lin E, Yu Y, Martin S, Hafner M, Haibe-Kains B. Mammoliti A, et al. Among authors: mer as. Nat Commun. 2021 Oct 4;12(1):5797. doi: 10.1038/s41467-021-25974-w. Nat Commun. 2021. PMID: 34608132 Free PMC article.
Assessing therapy response in patient-derived xenografts.
Ortmann J, Rampášek L, Tai E, Mer AS, Shi R, Stewart EL, Mascaux C, Fares A, Pham NA, Beri G, Eeles C, Tkachuk D, Ho C, Sakashita S, Weiss J, Jiang X, Liu G, Cescon DW, O'Brien CA, Guo S, Tsao MS, Haibe-Kains B, Goldenberg A. Ortmann J, et al. Among authors: mer as. Sci Transl Med. 2021 Nov 17;13(620):eabf4969. doi: 10.1126/scitranslmed.abf4969. Epub 2021 Nov 17. Sci Transl Med. 2021. PMID: 34788078
Ontogeny and Vulnerabilities of Drug-Tolerant Persisters in HER2+ Breast Cancer.
Chang CA, Jen J, Jiang S, Sayad A, Mer AS, Brown KR, Nixon AML, Dhabaria A, Tang KH, Venet D, Sotiriou C, Deng J, Wong KK, Adams S, Meyn P, Heguy A, Skok JA, Tsirigos A, Ueberheide B, Moffat J, Singh A, Haibe-Kains B, Khodadadi-Jamayran A, Neel BG. Chang CA, et al. Among authors: mer as. Cancer Discov. 2022 Apr 1;12(4):1022-1045. doi: 10.1158/2159-8290.CD-20-1265. Cancer Discov. 2022. PMID: 34911733 Free PMC article.
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