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Page 1
Synthetic development of a broadly neutralizing antibody against snake venom long-chain α-neurotoxins.
Khalek IS, Senji Laxme RR, Nguyen YTK, Khochare S, Patel RN, Woehl J, Smith JM, Saye-Francisco K, Kim Y, Misson Mindrebo L, Tran Q, Kędzior M, Boré E, Limbo O, Verma M, Stanfield RL, Menzies SK, Ainsworth S, Harrison RA, Burton DR, Sok D, Wilson IA, Casewell NR, Sunagar K, Jardine JG. Khalek IS, et al. Among authors: menzies sk. Sci Transl Med. 2024 Feb 21;16(735):eadk1867. doi: 10.1126/scitranslmed.adk1867. Epub 2024 Feb 21. Sci Transl Med. 2024. PMID: 38381847
An analysis of preclinical efficacy testing of antivenoms for sub-Saharan Africa: Inadequate independent scrutiny and poor-quality reporting are barriers to improving snakebite treatment and management.
Ainsworth S, Menzies SK, Casewell NR, Harrison RA. Ainsworth S, et al. Among authors: menzies sk. PLoS Negl Trop Dis. 2020 Aug 20;14(8):e0008579. doi: 10.1371/journal.pntd.0008579. eCollection 2020 Aug. PLoS Negl Trop Dis. 2020. PMID: 32817682 Free PMC article.
Two snakebite antivenoms have potential to reduce Eswatini's dependency upon a single, increasingly unavailable product: Results of preclinical efficacy testing.
Menzies SK, Litschka-Koen T, Edge RJ, Alsolaiss J, Crittenden E, Hall SR, Westhorpe A, Thomas B, Murray J, Shongwe N, Padidar S, Lalloo DG, Casewell NR, Pons J, Harrison RA. Menzies SK, et al. PLoS Negl Trop Dis. 2022 Sep 15;16(9):e0010496. doi: 10.1371/journal.pntd.0010496. eCollection 2022 Sep. PLoS Negl Trop Dis. 2022. PMID: 36108067 Free PMC article.
Livestock herding and Fulani ethnicity are a combined risk factor for development of early adverse reactions to antivenom treatment: Findings from a cross-sectional study in Nigeria.
Menzies SK, Thomas AO, Tianyi FL, Abubakar SB, Nasidi A, Durfa N, Patel R, Trelfa A, Lalloo DG, Habib AG, Harrison RA. Menzies SK, et al. PLoS Negl Trop Dis. 2021 Aug 12;15(8):e0009518. doi: 10.1371/journal.pntd.0009518. eCollection 2021 Aug. PLoS Negl Trop Dis. 2021. PMID: 34383742 Free PMC article.
In vitro and in vivo preclinical venom inhibition assays identify metalloproteinase inhibiting drugs as potential future treatments for snakebite envenoming by Dispholidus typus.
Menzies SK, Clare RH, Xie C, Westhorpe A, Hall SR, Edge RJ, Alsolaiss J, Crittenden E, Marriott AE, Harrison RA, Kool J, Casewell NR. Menzies SK, et al. Toxicon X. 2022 Mar 18;14:100118. doi: 10.1016/j.toxcx.2022.100118. eCollection 2022 Jun. Toxicon X. 2022. PMID: 35321116 Free PMC article.
ADDovenom: Thermostable Protein-Based ADDomer Nanoparticles as New Therapeutics for Snakebite Envenoming.
Menzies SK, Arinto-Garcia R, Amorim FG, Cardoso IA, Abada C, Crasset T, Durbesson F, Edge RJ, El-Kazzi P, Hall S, Redureau D, Stenner R, Boldrini-França J, Sun H, Roldão A, Alves PM, Harrison RA, Vincentelli R, Berger I, Quinton L, Casewell NR, Schaffitzel C. Menzies SK, et al. Toxins (Basel). 2023 Nov 28;15(12):673. doi: 10.3390/toxins15120673. Toxins (Basel). 2023. PMID: 38133177 Free PMC article.
African polyvalent antivenom can maintain pharmacological stability and ability to neutralise murine venom lethality for decades post-expiry: evidence for increasing antivenom shelf life to aid in alleviating chronic shortages.
Solano G, Cunningham S, Edge RJ, Duran G, Sanchez A, Villalta M, Clare RH, Wilkinson MC, Marriott AE, Abada C, Menzies SK, Keen M, Lalloo DG, Stienstra Y, Abouyannis M, Casewell NR, León G, Ainsworth S. Solano G, et al. Among authors: menzies sk. BMJ Glob Health. 2024 Mar 13;9(3):e014813. doi: 10.1136/bmjgh-2023-014813. BMJ Glob Health. 2024. PMID: 38485142 Free PMC article.
19 results