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Novel non-covalent LSD1 inhibitors endowed with anticancer effects in leukemia and solid tumor cellular models.
Menna M, Fiorentino F, Marrocco B, Lucidi A, Tomassi S, Cilli D, Romanenghi M, Cassandri M, Pomella S, Pezzella M, Del Bufalo D, Zeya Ansari MS, Tomašević N, Mladenović M, Viviano M, Sbardella G, Rota R, Trisciuoglio D, Minucci S, Mattevi A, Rotili D, Mai A. Menna M, et al. Eur J Med Chem. 2022 Jul 5;237:114410. doi: 10.1016/j.ejmech.2022.114410. Epub 2022 Apr 27. Eur J Med Chem. 2022. PMID: 35525212
Sirtuin modulators: past, present, and future perspectives.
Fiorentino F, Mautone N, Menna M, D'Acunzo F, Mai A, Rotili D. Fiorentino F, et al. Among authors: menna m. Future Med Chem. 2022 Jun;14(12):915-939. doi: 10.4155/fmc-2022-0031. Epub 2022 May 18. Future Med Chem. 2022. PMID: 35583203 Free PMC article. Review.
Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile-Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence.
Zhou J, Horton JR, Menna M, Fiorentino F, Ren R, Yu D, Hajian T, Vedadi M, Mazzoccanti G, Ciogli A, Weinhold E, Hüben M, Blumenthal RM, Zhang X, Mai A, Rotili D, Cheng X. Zhou J, et al. Among authors: menna m. J Med Chem. 2023 Jan 12;66(1):934-950. doi: 10.1021/acs.jmedchem.2c01789. Epub 2022 Dec 29. J Med Chem. 2023. PMID: 36581322 Free PMC article.
First-in-Class Selective Inhibitors of the Lysine Acetyltransferase KAT8.
Fiorentino F, Sementilli S, Menna M, Turrisi F, Tomassi S, Pellegrini FR, Iuzzolino A, D'Acunzo F, Feoli A, Wapenaar H, Taraglio S, Fraschetti C, Del Bufalo D, Sbardella G, Dekker FJ, Paiardini A, Trisciuoglio D, Mai A, Rotili D. Fiorentino F, et al. Among authors: menna m. J Med Chem. 2023 May 25;66(10):6591-6616. doi: 10.1021/acs.jmedchem.2c01937. Epub 2023 May 8. J Med Chem. 2023. PMID: 37155735 Free PMC article.
Specific Inhibitors of Mitochondrial Deacylase Sirtuin 4 Endowed with Cellular Activity.
Pannek M, Alhalabi Z, Tomaselli D, Menna M, Fiorentino F, Robaa D, Weyand M, Puhlmann M, Tomassi S, Barreca F, Tafani M, Zaganjor E, Haigis MC, Sippl W, Rotili D, Mai A, Steegborn C. Pannek M, et al. Among authors: menna m. J Med Chem. 2024 Feb 8;67(3):1843-1860. doi: 10.1021/acs.jmedchem.3c01496. Epub 2024 Jan 22. J Med Chem. 2024. PMID: 38253001
Searching for Novel Sources of Hydrogen Sulfide Donors: Chemical Profiling of Polycarpa aurata Extract and Evaluation of the Anti-Inflammatory Effects.
Casertano M, Esposito E, Bello I, Indolfi C, Putra MY, Di Cesare Mannelli L, Ghelardini C, Menna M, Sorrentino R, Cirino G, d'Emmanuele di Villa Bianca R, Imperatore C, Panza E, Mitidieri E. Casertano M, et al. Among authors: menna m. Mar Drugs. 2023 Dec 15;21(12):641. doi: 10.3390/md21120641. Mar Drugs. 2023. PMID: 38132963 Free PMC article.
179 results