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Microglial overexpression of fALS-linked mutant SOD1 induces SOD1 processing impairment, activation and neurotoxicity and is counteracted by the autophagy inducer trehalose.
Massenzio F, Peña-Altamira E, Petralla S, Virgili M, Zuccheri G, Miti A, Polazzi E, Mengoni I, Piffaretti D, Monti B. Massenzio F, et al. Among authors: mengoni i. Biochim Biophys Acta Mol Basis Dis. 2018 Dec;1864(12):3771-3785. doi: 10.1016/j.bbadis.2018.10.013. Epub 2018 Oct 10. Biochim Biophys Acta Mol Basis Dis. 2018. PMID: 30315929 Free article.
Release of soluble and vesicular purine nucleoside phosphorylase from rat astrocytes and microglia induced by pro-inflammatory stimulation with extracellular ATP via P2X7 receptors.
Peña-Altamira LE, Polazzi E, Giuliani P, Beraudi A, Massenzio F, Mengoni I, Poli A, Zuccarini M, Ciccarelli R, Di Iorio P, Virgili M, Monti B, Caciagli F. Peña-Altamira LE, et al. Among authors: mengoni i. Neurochem Int. 2018 May;115:37-49. doi: 10.1016/j.neuint.2017.10.010. Epub 2017 Oct 20. Neurochem Int. 2018. PMID: 29061383