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Genome-wide association meta-analysis identifies 48 risk variants and highlights the role of the stria vascularis in hearing loss.
Trpchevska N, Freidin MB, Broer L, Oosterloo BC, Yao S, Zhou Y, Vona B, Bishop C, Bizaki-Vallaskangas A, Canlon B, Castellana F, Chasman DI, Cherny S, Christensen K, Concas MP, Correa A, Elkon R; Estonian Biobank Research Team; Mengel-From J, Gao Y, Giersch ABS, Girotto G, Gudjonsson A, Gudnason V, Heard-Costa NL, Hertzano R, Hjelmborg JVB, Hjerling-Leffler J, Hoffman HJ, Kaprio J, Kettunen J, Krebs K, Kähler AK, Lallemend F, Launer LJ, Lee IM, Leonard H, Li CM, Lowenheim H, Magnusson PKE, van Meurs J, Milani L, Morton CC, Mäkitie A, Nalls MA, Nardone GG, Nygaard M, Palviainen T, Pratt S, Quaranta N, Rämö J, Saarentaus E, Sardone R, Satizabal CL, Schweinfurth JM, Seshadri S, Shiroma E, Shulman E, Simonsick E, Spankovich C, Tropitzsch A, Lauschke VM, Sullivan PF, Goedegebure A, Cederroth CR, Williams FMK, Nagtegaal AP. Trpchevska N, et al. Am J Hum Genet. 2022 Jun 2;109(6):1077-1091. doi: 10.1016/j.ajhg.2022.04.010. Epub 2022 May 16. Am J Hum Genet. 2022. PMID: 35580588 Free PMC article.
CLU genetic variants and cognitive decline among elderly and oldest old.
Mengel-From J, Thinggaard M, Lindahl-Jacobsen R, McGue M, Christensen K, Christiansen L. Mengel-From J, et al. PLoS One. 2013 Nov 14;8(11):e79105. doi: 10.1371/journal.pone.0079105. eCollection 2013. PLoS One. 2013. PMID: 24244428 Free PMC article. Clinical Trial.
Human longevity and variation in DNA damage response and repair: study of the contribution of sub-processes using competitive gene-set analysis.
Debrabant B, Soerensen M, Flachsbart F, Dato S, Mengel-From J, Stevnsner T, Bohr VA, Kruse TA, Schreiber S, Nebel A, Christensen K, Tan Q, Christiansen L. Debrabant B, et al. Eur J Hum Genet. 2014 Sep;22(9):1131-6. doi: 10.1038/ejhg.2013.299. Epub 2014 Feb 12. Eur J Hum Genet. 2014. PMID: 24518833 Free PMC article.
The APP A673T frequency differs between Nordic countries.
Mengel-From J, Jeune B, Pentti T, McGue M, Christensen K, Christiansen L. Mengel-From J, et al. Neurobiol Aging. 2015 Oct;36(10):2909.e1-4. doi: 10.1016/j.neurobiolaging.2015.07.011. Epub 2015 Jul 11. Neurobiol Aging. 2015. PMID: 26239177 Free PMC article.
65 results