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Discovery of BAY-985, a Highly Selective TBK1/IKKε Inhibitor.
Lefranc J, Schulze VK, Hillig RC, Briem H, Prinz F, Mengel A, Heinrich T, Balint J, Rengachari S, Irlbacher H, Stöckigt D, Bömer U, Bader B, Gradl SN, Nising CF, von Nussbaum F, Mumberg D, Panne D, Wengner AM. Lefranc J, et al. Among authors: mengel a. J Med Chem. 2020 Jan 23;63(2):601-612. doi: 10.1021/acs.jmedchem.9b01460. Epub 2020 Jan 10. J Med Chem. 2020. PMID: 31859507
Inhibition of BUB1 Kinase by BAY 1816032 Sensitizes Tumor Cells toward Taxanes, ATR, and PARP Inhibitors In Vitro and In Vivo.
Siemeister G, Mengel A, Fernández-Montalván AE, Bone W, Schröder J, Zitzmann-Kolbe S, Briem H, Prechtl S, Holton SJ, Mönning U, von Ahsen O, Johanssen S, Cleve A, Pütter V, Hitchcock M, von Nussbaum F, Brands M, Ziegelbauer K, Mumberg D. Siemeister G, et al. Among authors: mengel a. Clin Cancer Res. 2019 Feb 15;25(4):1404-1414. doi: 10.1158/1078-0432.CCR-18-0628. Epub 2018 Nov 14. Clin Cancer Res. 2019. PMID: 30429199
Design and synthesis of macrocyclic inhibitors of phosphatase cdc25B.
Bäurle S, Blume T, Günther J, Henschel D, Hillig RC, Husemann M, Mengel A, Parchmann C, Schmid E, Skuballa W. Bäurle S, et al. Among authors: mengel a. Bioorg Med Chem Lett. 2004 Apr 5;14(7):1673-7. doi: 10.1016/j.bmcl.2004.01.052. Bioorg Med Chem Lett. 2004. PMID: 15026048
The role of mitogen-activated protein kinase-activated protein kinase 2 in the p38/TNF-alpha pathway of systemic and cutaneous inflammation.
Schottelius AJ, Zügel U, Döcke WD, Zollner TM, Röse L, Mengel A, Buchmann B, Becker A, Grütz G, Naundorf S, Friedrich A, Gaestel M, Asadullah K. Schottelius AJ, et al. Among authors: mengel a. J Invest Dermatol. 2010 Feb;130(2):481-91. doi: 10.1038/jid.2009.218. Epub 2009 Aug 6. J Invest Dermatol. 2010. PMID: 19657354 Free article.
112 results