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Absence of Functional Nav1.8 Channels in Non-diseased Atrial and Ventricular Cardiomyocytes.
Casini S, Marchal GA, Kawasaki M, Nariswari FA, Portero V, van den Berg NWE, Guan K, Driessen AHG, Veldkamp MW, Mengarelli I, de Groot JR, Verkerk AO, Remme CA. Casini S, et al. Among authors: mengarelli i. Cardiovasc Drugs Ther. 2019 Dec;33(6):649-660. doi: 10.1007/s10557-019-06925-6. Cardiovasc Drugs Ther. 2019. PMID: 31916131 Free PMC article.
The Brugada Syndrome Susceptibility Gene HEY2 Modulates Cardiac Transmural Ion Channel Patterning and Electrical Heterogeneity.
Veerman CC, Podliesna S, Tadros R, Lodder EM, Mengarelli I, de Jonge B, Beekman L, Barc J, Wilders R, Wilde AAM, Boukens BJ, Coronel R, Verkerk AO, Remme CA, Bezzina CR. Veerman CC, et al. Among authors: mengarelli i. Circ Res. 2017 Aug 18;121(5):537-548. doi: 10.1161/CIRCRESAHA.117.310959. Epub 2017 Jun 21. Circ Res. 2017. PMID: 28637782
Switch From Fetal to Adult SCN5A Isoform in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Unmasks the Cellular Phenotype of a Conduction Disease-Causing Mutation.
Veerman CC, Mengarelli I, Lodder EM, Kosmidis G, Bellin M, Zhang M, Dittmann S, Guan K, Wilde AAM, Schulze-Bahr E, Greber B, Bezzina CR, Verkerk AO. Veerman CC, et al. Among authors: mengarelli i. J Am Heart Assoc. 2017 Jul 24;6(7):e005135. doi: 10.1161/JAHA.116.005135. J Am Heart Assoc. 2017. PMID: 28739862 Free PMC article.
Genetic variation in GNB5 causes bradycardia by augmenting the cholinergic response via increased acetylcholine-activated potassium current (IK,ACh).
Veerman CC, Mengarelli I, Koopman CD, Wilders R, van Amersfoorth SC, Bakker D, Wolswinkel R, Hababa M, de Boer TP, Guan K, Milnes J, Lodder EM, Bakkers J, Verkerk AO, Bezzina CR. Veerman CC, et al. Among authors: mengarelli i. Dis Model Mech. 2019 Jul 9;12(7):dmm037994. doi: 10.1242/dmm.037994. Dis Model Mech. 2019. PMID: 31208990 Free PMC article.
18 results