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DNA repair mechanisms that promote insertion-deletion events during immunoglobulin gene diversification.
Hao Q, Zhan C, Lian C, Luo S, Cao W, Wang B, Xie X, Ye X, Gui T, Voena C, Pighi C, Wang Y, Tian Y, Wang X, Dai P, Cai Y, Liu X, Ouyang S, Sun S, Hu Q, Liu J, Ye Y, Zhao J, Lu A, Wang JY, Huang C, Su B, Meng FL, Chiarle R, Pan-Hammarström Q, Yeap LS. Hao Q, et al. Among authors: meng fl. Sci Immunol. 2023 Mar 31;8(81):eade1167. doi: 10.1126/sciimmunol.ade1167. Epub 2023 Mar 24. Sci Immunol. 2023. PMID: 36961908 Free PMC article.
Phosphatidylinositol 3-kinase δ blockade increases genomic instability in B cells.
Compagno M, Wang Q, Pighi C, Cheong TC, Meng FL, Poggio T, Yeap LS, Karaca E, Blasco RB, Langellotto F, Ambrogio C, Voena C, Wiestner A, Kasar SN, Brown JR, Sun J, Wu CJ, Gostissa M, Alt FW, Chiarle R. Compagno M, et al. Among authors: meng fl. Nature. 2017 Feb 23;542(7642):489-493. doi: 10.1038/nature21406. Epub 2017 Feb 15. Nature. 2017. PMID: 28199309 Free PMC article.
The mTOR-S6K pathway links growth signalling to DNA damage response by targeting RNF168.
Xie X, Hu H, Tong X, Li L, Liu X, Chen M, Yuan H, Xie X, Li Q, Zhang Y, Ouyang H, Wei M, Huang J, Liu P, Gan W, Liu Y, Xie A, Kuai X, Chirn GW, Zhou H, Zeng R, Hu R, Qin J, Meng FL, Wei W, Ji H, Gao D. Xie X, et al. Among authors: meng fl. Nat Cell Biol. 2018 Mar;20(3):320-331. doi: 10.1038/s41556-017-0033-8. Epub 2018 Feb 5. Nat Cell Biol. 2018. PMID: 29403037 Free PMC article.
Parp3 promotes long-range end joining in murine cells.
Layer JV, Cleary JP, Brown AJ, Stevenson KE, Morrow SN, Van Scoyk A, Blasco RB, Karaca E, Meng FL, Frock RL, Tivey T, Kim S, Fuchs H, Chiarle R, Alt FW, Roberts SA, Weinstock DM, Day TA. Layer JV, et al. Among authors: meng fl. Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):10076-10081. doi: 10.1073/pnas.1801591115. Epub 2018 Sep 13. Proc Natl Acad Sci U S A. 2018. PMID: 30213852 Free PMC article.
ERCC6L2 promotes DNA orientation-specific recombination in mammalian cells.
Liu X, Liu T, Shang Y, Dai P, Zhang W, Lee BJ, Huang M, Yang D, Wu Q, Liu LD, Zheng X, Zhou BO, Dong J, Yeap LS, Hu J, Xiao T, Zha S, Casellas R, Liu XS, Meng FL. Liu X, et al. Among authors: meng fl. Cell Res. 2020 Sep;30(9):732-744. doi: 10.1038/s41422-020-0328-3. Epub 2020 Apr 30. Cell Res. 2020. PMID: 32355287 Free PMC article.
150 results