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Discovery, optimization, and pharmacological characterization of novel heteroaroylphenylureas antagonists of C-C chemokine ligand 2 function.
Laborde E, Macsata RW, Meng F, Peterson BT, Robinson L, Schow SR, Simon RJ, Xu H, Baba K, Inagaki H, Ishiwata Y, Jomori T, Matsumoto Y, Miyachi A, Nakamura T, Okamoto M, Handel TM, Bernard CC. Laborde E, et al. Among authors: meng f. J Med Chem. 2011 Mar 24;54(6):1667-81. doi: 10.1021/jm1012903. Epub 2011 Feb 22. J Med Chem. 2011. PMID: 21341682 Free PMC article.
Discovery of 2-((2-methylbenzyl)thio)-6-oxo-4-(3,4,5-trimethoxyphenyl)-1,6-dihydropyrimidine-5-carbonitrile as a novel and effective bromodomain and extra-terminal (BET) inhibitor for the treatment of sepsis.
Chen X, Meng F, Zhang J, Zhang Z, Ye X, Zhang W, Tong Y, Ji X, Xu R, Xu XL, You QD, Jiang ZY. Chen X, et al. Among authors: meng f. Eur J Med Chem. 2022 Aug 5;238:114423. doi: 10.1016/j.ejmech.2022.114423. Epub 2022 May 8. Eur J Med Chem. 2022. PMID: 35544982
Essential role of glycoprotein Ibα in platelet activation.
Yan R, Xia Y, Zhou K, Liu J, Sun Y, He C, Ge X, Yang M, Sun C, Yuan L, Li S, Yang B, Meng F, Cao L, Ruan C, Dai K. Yan R, et al. Among authors: meng f. Blood Adv. 2024 May 3:bloodadvances.2023012308. doi: 10.1182/bloodadvances.2023012308. Online ahead of print. Blood Adv. 2024. PMID: 38701351
6,492 results