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Identification and characterization of the first fragment hits for SETDB1 Tudor domain.
Mader P, Mendoza-Sanchez R, Iqbal A, Dong A, Dobrovetsky E, Corless VB, Liew SK, Houliston SR, De Freitas RF, Smil D, Sena CCD, Kennedy S, Diaz DB, Wu H, Dombrovski L, Allali-Hassani A, Min J, Schapira M, Vedadi M, Brown PJ, Santhakumar V, Yudin AK, Arrowsmith CH. Mader P, et al. Among authors: mendoza sanchez r. Bioorg Med Chem. 2019 Sep 1;27(17):3866-3878. doi: 10.1016/j.bmc.2019.07.020. Epub 2019 Jul 12. Bioorg Med Chem. 2019. PMID: 31327677
Cyclols Revisited: Facile Synthesis of Medium-Sized Cyclic Peptides.
Mendoza-Sanchez R, Corless VB, Nguyen QNN, Bergeron-Brlek M, Frost J, Adachi S, Tantillo DJ, Yudin AK. Mendoza-Sanchez R, et al. Chemistry. 2017 Sep 27;23(54):13319-13322. doi: 10.1002/chem.201703616. Epub 2017 Aug 31. Chemistry. 2017. PMID: 28771904
Vitamin D receptor agonist/histone deacetylase inhibitor molecular hybrids.
Lamblin M, Dabbas B, Spingarn R, Mendoza-Sanchez R, Wang TT, An BS, Huang DC, Kremer R, White JH, Gleason JL. Lamblin M, et al. Among authors: mendoza sanchez r. Bioorg Med Chem. 2010 Jun 1;18(11):4119-37. doi: 10.1016/j.bmc.2010.03.078. Epub 2010 Apr 7. Bioorg Med Chem. 2010. PMID: 20452225
Role of SUMOylation in full antiestrogenicity.
Hilmi K, Hussein N, Mendoza-Sanchez R, El-Ezzy M, Ismail H, Durette C, Bail M, Rozendaal MJ, Bouvier M, Thibault P, Gleason JL, Mader S. Hilmi K, et al. Among authors: mendoza sanchez r. Mol Cell Biol. 2012 Oct;32(19):3823-37. doi: 10.1128/MCB.00290-12. Epub 2012 Jul 23. Mol Cell Biol. 2012. PMID: 22826433 Free PMC article.
Integrating medicinal chemistry, organic/combinatorial chemistry, and computational chemistry for the discovery of selective estrogen receptor modulators with Forecaster, a novel platform for drug discovery.
Therrien E, Englebienne P, Arrowsmith AG, Mendoza-Sanchez R, Corbeil CR, Weill N, Campagna-Slater V, Moitessier N. Therrien E, et al. Among authors: mendoza sanchez r. J Chem Inf Model. 2012 Jan 23;52(1):210-24. doi: 10.1021/ci2004779. Epub 2011 Dec 15. J Chem Inf Model. 2012. PMID: 22133077
Vesicular trafficking is a key determinant of the statin response in acute myeloid leukemia.
Krosl J, Bordeleau ME, Moison C, MacRae T, Boivin I, Mayotte N, Gracias D, Baccelli I, Lavallée VP, Bisaillon R, Lehnertz B, Mendoza-Sanchez R, Ruel R, Bertomeu T, Coulombe-Huntington J, Boucher G, Noronha N, Pabst C, Tyers M, Gendron P, Lemieux S, Barabé F, Marinier A, Hébert J, Sauvageau G. Krosl J, et al. Among authors: mendoza sanchez r. Blood Adv. 2022 Jan 25;6(2):509-514. doi: 10.1182/bloodadvances.2021006047. Blood Adv. 2022. PMID: 34731885 Free PMC article.
SF3B1 mutations provide genetic vulnerability to copper ionophores in human acute myeloid leukemia.
Moison C, Gracias D, Schmitt J, Girard S, Spinella JF, Fortier S, Boivin I, Mendoza-Sanchez R, Thavonekham B, MacRae T, Mayotte N, Bonneil E, Wittman M, Carmichael J, Ruel R, Thibault P, Hébert J, Marinier A, Sauvageau G. Moison C, et al. Among authors: mendoza sanchez r. Sci Adv. 2024 Mar 22;10(12):eadl4018. doi: 10.1126/sciadv.adl4018. Epub 2024 Mar 22. Sci Adv. 2024. PMID: 38517966 Free PMC article.
11 results