Mendoza A - Search Results

1

Inhibition of NAD+-Dependent Metabolic Processes Induces Cellular Necrosis and Tumor Regression in Rhabdomyosarcoma Models.

McKay-Corkum GB, Collins VJ, Yeung C, Ito T, Issaq SH, Holland D, Vulikh K, Zhang Y, Lee U, Lei H, Mendoza A, Shern JF, Yohe ME, Yamamoto K, Wilson K, Ji J, Karim BO, Thomas CJ, Krishna MC, Neckers LM, Heske CM. McKay-Corkum GB, et al. Among authors: mendoza a. Clin Cancer Res. 2023 Nov 1;29(21):4479-4491. doi: 10.1158/1078-0432.CCR-23-0200. Clin Cancer Res. 2023. PMID: 37616468 Free PMC article.

2

The membrane-cytoskeleton linker ezrin is necessary for osteosarcoma metastasis.

Khanna C, Wan X, Bose S, Cassaday R, Olomu O, Mendoza A, Yeung C, Gorlick R, Hewitt SM, Helman LJ. Khanna C, et al. Among authors: mendoza a. Nat Med. 2004 Feb;10(2):182-6. doi: 10.1038/nm982. Epub 2004 Jan 4. Nat Med. 2004. PMID: 14704791

3

Inhibition of the CXCR4/CXCL12 chemokine pathway reduces the development of murine pulmonary metastases.

Kim SY, Lee CH, Midura BV, Yeung C, Mendoza A, Hong SH, Ren L, Wong D, Korz W, Merzouk A, Salari H, Zhang H, Hwang ST, Khanna C, Helman LJ. Kim SY, et al. Among authors: mendoza a. Clin Exp Metastasis. 2008;25(3):201-11. doi: 10.1007/s10585-007-9133-3. Epub 2007 Dec 11. Clin Exp Metastasis. 2008. PMID: 18071913 Free PMC article.

4

Identification of an inhibitor of the EWS-FLI1 oncogenic transcription factor by high-throughput screening.

Grohar PJ, Woldemichael GM, Griffin LB, Mendoza A, Chen QR, Yeung C, Currier DG, Davis S, Khanna C, Khan J, McMahon JB, Helman LJ. Grohar PJ, et al. Among authors: mendoza a. J Natl Cancer Inst. 2011 Jun 22;103(12):962-78. doi: 10.1093/jnci/djr156. Epub 2011 Jun 8. J Natl Cancer Inst. 2011. PMID: 21653923 Free PMC article.

5

Dual targeting of EWS-FLI1 activity and the associated DNA damage response with trabectedin and SN38 synergistically inhibits Ewing sarcoma cell growth.

Grohar PJ, Segars LE, Yeung C, Pommier Y, D'Incalci M, Mendoza A, Helman LJ. Grohar PJ, et al. Among authors: mendoza a. Clin Cancer Res. 2014 Mar 1;20(5):1190-203. doi: 10.1158/1078-0432.CCR-13-0901. Epub 2013 Nov 25. Clin Cancer Res. 2014. PMID: 24277455 Free PMC article.

6

IGF-1R Inhibition Activates a YES/SFK Bypass Resistance Pathway: Rational Basis for Co-Targeting IGF-1R and Yes/SFK Kinase in Rhabdomyosarcoma.

Wan X, Yeung C, Heske C, Mendoza A, Helman LJ. Wan X, et al. Among authors: mendoza a. Neoplasia. 2015 Apr;17(4):358-66. doi: 10.1016/j.neo.2015.03.001. Neoplasia. 2015. PMID: 25925378 Free PMC article.

7

Aurora B kinase is a potent and selective target in MYCN-driven neuroblastoma.

Bogen D, Wei JS, Azorsa DO, Ormanoglu P, Buehler E, Guha R, Keller JM, Mathews Griner LA, Ferrer M, Song YK, Liao H, Mendoza A, Gryder BE, Sindri S, He J, Wen X, Zhang S, Shern JF, Yohe ME, Taschner-Mandl S, Shohet JM, Thomas CJ, Martin SE, Ambros PF, Khan J. Bogen D, et al. Among authors: mendoza a. Oncotarget. 2015 Nov 3;6(34):35247-62. doi: 10.18632/oncotarget.6208. Oncotarget. 2015. PMID: 26497213 Free PMC article.

8

mTOR Inhibition Mitigates Enhanced mRNA Translation Associated with the Metastatic Phenotype of Osteosarcoma Cells In Vivo.

Morrow JJ, Mendoza A, Koyen A, Lizardo MM, Ren L, Waybright TJ, Hansen RJ, Gustafson DL, Zhou M, Fan TM, Scacheri PC, Khanna C. Morrow JJ, et al. Among authors: mendoza a. Clin Cancer Res. 2016 Dec 15;22(24):6129-6141. doi: 10.1158/1078-0432.CCR-16-0326. Epub 2016 Jun 24. Clin Cancer Res. 2016. PMID: 27342399 Free PMC article.

9

STA-8666, a novel HSP90 inhibitor/SN-38 drug conjugate, causes complete tumor regression in preclinical mouse models of pediatric sarcoma.

Heske CM, Mendoza A, Edessa LD, Baumgart JT, Lee S, Trepel J, Proia DA, Neckers L, Helman LJ. Heske CM, et al. Among authors: mendoza a. Oncotarget. 2016 Oct 4;7(40):65540-65552. doi: 10.18632/oncotarget.11869. Oncotarget. 2016. PMID: 27608846 Free PMC article.

10

The Role of PDGFR-β Activation in Acquired Resistance to IGF-1R Blockade in Preclinical Models of Rhabdomyosarcoma.

Heske CM, Yeung C, Mendoza A, Baumgart JT, Edessa LD, Wan X, Helman LJ. Heske CM, et al. Among authors: mendoza a. Transl Oncol. 2016 Dec;9(6):540-547. doi: 10.1016/j.tranon.2016.09.002. Epub 2016 Nov 16. Transl Oncol. 2016. PMID: 27835791 Free PMC article.

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