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H3.3-G34R Mutation-Mediated Epigenetic Reprogramming Leads to Enhanced Efficacy of Immune Stimulatory Gene Therapy in Pediatric High-Grade Gliomas.
Garcia-Fabiani MB, Haase S, Banerjee K, McClellan B, Zhu Z, Mujeeb A, Li Y, Yu J, Kadiyala P, Taher A, Núñez FJ, Alghamri MS, Comba A, Mendez FM, Nicola Candia AJ, Salazar B, Koschmann C, Nunez FM, Edwards M, Qin T, Sartor MA, Lowenstein PR, Castro MG. Garcia-Fabiani MB, et al. Among authors: mendez fm. bioRxiv [Preprint]. 2023 Jun 13:2023.06.13.544658. doi: 10.1101/2023.06.13.544658. bioRxiv. 2023. PMID: 37398299 Free PMC article. Preprint.
Genetically Engineered Mouse Model of Brainstem High-Grade Glioma.
Nunez FM, Gauss JC, Mendez FM, Haase S, Lowenstein PR, Castro MG. Nunez FM, et al. Among authors: mendez fm. STAR Protoc. 2020 Nov 25;1(3):100165. doi: 10.1016/j.xpro.2020.100165. eCollection 2020 Dec 18. STAR Protoc. 2020. PMID: 33377059 Free PMC article.
IDH1-R132H acts as a tumor suppressor in glioma via epigenetic up-regulation of the DNA damage response.
Núñez FJ, Mendez FM, Kadiyala P, Alghamri MS, Savelieff MG, Garcia-Fabiani MB, Haase S, Koschmann C, Calinescu AA, Kamran N, Saxena M, Patel R, Carney S, Guo MZ, Edwards M, Ljungman M, Qin T, Sartor MA, Tagett R, Venneti S, Brosnan-Cashman J, Meeker A, Gorbunova V, Zhao L, Kremer DM, Zhang L, Lyssiotis CA, Jones L, Herting CJ, Ross JL, Hambardzumyan D, Hervey-Jumper S, Figueroa ME, Lowenstein PR, Castro MG. Núñez FJ, et al. Among authors: mendez fm. Sci Transl Med. 2019 Feb 13;11(479):eaaq1427. doi: 10.1126/scitranslmed.aaq1427. Sci Transl Med. 2019. PMID: 30760578 Free PMC article.
Mutant ATRX: uncovering a new therapeutic target for glioma.
Haase S, Garcia-Fabiani MB, Carney S, Altshuler D, Núñez FJ, Méndez FM, Núñez F, Lowenstein PR, Castro MG. Haase S, et al. Among authors: mendez fm. Expert Opin Ther Targets. 2018 Jul;22(7):599-613. doi: 10.1080/14728222.2018.1487953. Epub 2018 Jun 20. Expert Opin Ther Targets. 2018. PMID: 29889582 Free PMC article. Review.