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Effect of ionizing radiation exposure on Trypanosoma cruzi ubiquitin-proteasome system.
Cerqueira PG, Passos-Silva DG, Vieira-da-Rocha JP, Mendes IC, de Oliveira KA, Oliveira CF, Vilela LF, Nagem RA, Cardoso J, Nardelli SC, Krieger MA, Franco GR, Macedo AM, Pena SD, Schenkman S, Gomes DA, Guerra-Sá R, Machado CR. Cerqueira PG, et al. Among authors: mendes ic. Mol Biochem Parasitol. 2017 Mar;212:55-67. doi: 10.1016/j.molbiopara.2017.01.005. Epub 2017 Jan 27. Mol Biochem Parasitol. 2017. PMID: 28137628 Free article.
Unveiling benznidazole's mechanism of action through overexpression of DNA repair proteins in Trypanosoma cruzi.
Rajão MA, Furtado C, Alves CL, Passos-Silva DG, de Moura MB, Schamber-Reis BL, Kunrath-Lima M, Zuma AA, Vieira-da-Rocha JP, Garcia JB, Mendes IC, Pena SD, Macedo AM, Franco GR, de Souza-Pinto NC, de Medeiros MH, Cruz AK, Motta MC, Teixeira SM, Machado CR. Rajão MA, et al. Among authors: mendes ic. Environ Mol Mutagen. 2014 May;55(4):309-21. doi: 10.1002/em.21839. Epub 2013 Dec 18. Environ Mol Mutagen. 2014. PMID: 24347026
The in vivo and in vitro roles of Trypanosoma cruzi Rad51 in the repair of DNA double strand breaks and oxidative lesions.
Gomes Passos Silva D, da Silva Santos S, Nardelli SC, Mendes IC, Freire ACG, Repolês BM, Resende BC, Costa-Silva HM, da Silva VS, Oliveira KA, Oliveira CFB, Vilela LFF, Nagem RAP, Franco GR, Macedo AM, Pena SDJ, Tahara EB, Sales Junior PA, Moreira DS, Teixeira SMR, McCulloch R, Virgilio S, Tosi LRO, Schenkman S, Andrade LO, Murta SMF, Machado CR. Gomes Passos Silva D, et al. Among authors: mendes ic. PLoS Negl Trop Dis. 2018 Nov 13;12(11):e0006875. doi: 10.1371/journal.pntd.0006875. eCollection 2018 Nov. PLoS Negl Trop Dis. 2018. PMID: 30422982 Free PMC article.
The DNA damage response is developmentally regulated in the African trypanosome.
Vieira-da-Rocha JP, Passos-Silva DG, Mendes IC, Rocha EA, Gomes DA, Machado CR, McCulloch R. Vieira-da-Rocha JP, et al. Among authors: mendes ic. DNA Repair (Amst). 2019 Jan;73:78-90. doi: 10.1016/j.dnarep.2018.11.005. Epub 2018 Nov 14. DNA Repair (Amst). 2019. PMID: 30470509 Free PMC article.
Oxidative stress and DNA lesions: the role of 8-oxoguanine lesions in Trypanosoma cruzi cell viability.
Aguiar PH, Furtado C, Repolês BM, Ribeiro GA, Mendes IC, Peloso EF, Gadelha FR, Macedo AM, Franco GR, Pena SD, Teixeira SM, Vieira LQ, Guarneri AA, Andrade LO, Machado CR. Aguiar PH, et al. Among authors: mendes ic. PLoS Negl Trop Dis. 2013 Jun 13;7(6):e2279. doi: 10.1371/journal.pntd.0002279. Print 2013. PLoS Negl Trop Dis. 2013. PMID: 23785540 Free PMC article.
Functional characterization of 8-oxoguanine DNA glycosylase of Trypanosoma cruzi.
Furtado C, Kunrath-Lima M, Rajão MA, Mendes IC, de Moura MB, Campos PC, Macedo AM, Franco GR, Pena SD, Teixeira SM, Van Houten B, Machado CR. Furtado C, et al. Among authors: mendes ic. PLoS One. 2012;7(8):e42484. doi: 10.1371/journal.pone.0042484. Epub 2012 Aug 2. PLoS One. 2012. PMID: 22876325 Free PMC article.
Nucleotide excision repair in Trypanosoma brucei: specialization of transcription-coupled repair due to multigenic transcription.
Machado CR, Vieira-da-Rocha JP, Mendes IC, Rajão MA, Marcello L, Bitar M, Drummond MG, Grynberg P, Oliveira DA, Marques C, Van Houten B, McCulloch R. Machado CR, et al. Among authors: mendes ic. Mol Microbiol. 2014 May;92(4):756-76. doi: 10.1111/mmi.12589. Epub 2014 Apr 24. Mol Microbiol. 2014. PMID: 24661334 Free PMC article.
The recombinase Rad51 plays a key role in events of genetic exchange in Trypanosoma cruzi.
Alves CL, Repolês BM, da Silva MS, Mendes IC, Marin PA, Aguiar PHN, Santos SDS, Franco GR, Macedo AM, Pena SDJ, Andrade LO, Guarneri AA, Tahara EB, Elias MC, Machado CR. Alves CL, et al. Among authors: mendes ic. Sci Rep. 2018 Sep 6;8(1):13335. doi: 10.1038/s41598-018-31541-z. Sci Rep. 2018. PMID: 30190603 Free PMC article.
47 results