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Reduced endoglin activity limits cardiac fibrosis and improves survival in heart failure.
Kapur NK, Wilson S, Yunis AA, Qiao X, Mackey E, Paruchuri V, Baker C, Aronovitz MJ, Karumanchi SA, Letarte M, Kass DA, Mendelsohn ME, Karas RH. Kapur NK, et al. Among authors: mendelsohn me. Circulation. 2012 Jun 5;125(22):2728-38. doi: 10.1161/CIRCULATIONAHA.111.080002. Epub 2012 May 16. Circulation. 2012. PMID: 22592898 Free PMC article.
Mutation of the protein kinase I alpha leucine zipper domain produces hypertension and progressive left ventricular hypertrophy: a novel mouse model of age-dependent hypertensive heart disease.
Blanton RM, Takimoto E, Aronovitz M, Thoonen R, Kass DA, Karas RH, Mendelsohn ME. Blanton RM, et al. Among authors: mendelsohn me. J Gerontol A Biol Sci Med Sci. 2013 Nov;68(11):1351-5. doi: 10.1093/gerona/glt042. Epub 2013 May 8. J Gerontol A Biol Sci Med Sci. 2013. PMID: 23657971 Free PMC article.
The mitochondrial regulator PGC1α is induced by cGMP-PKG signaling and mediates the protective effects of phosphodiesterase 5 inhibition in heart failure.
Zhu G, Ueda K, Hashimoto M, Zhang M, Sasaki M, Kariya T, Sasaki H, Kaludercic N, Lee DI, Bedja D, Gabrielson M, Yuan Y, Paolocci N, Blanton RM, Karas RH, Mendelsohn ME, O'Rourke B, Kass DA, Takimoto E. Zhu G, et al. Among authors: mendelsohn me. FEBS Lett. 2022 Jan;596(1):17-28. doi: 10.1002/1873-3468.14228. Epub 2021 Nov 19. FEBS Lett. 2022. PMID: 34778969 Free PMC article.
High blood pressure arising from a defect in vascular function.
Michael SK, Surks HK, Wang Y, Zhu Y, Blanton R, Jamnongjit M, Aronovitz M, Baur W, Ohtani K, Wilkerson MK, Bonev AD, Nelson MT, Karas RH, Mendelsohn ME. Michael SK, et al. Among authors: mendelsohn me. Proc Natl Acad Sci U S A. 2008 May 6;105(18):6702-7. doi: 10.1073/pnas.0802128105. Epub 2008 Apr 30. Proc Natl Acad Sci U S A. 2008. PMID: 18448676 Free PMC article.
145 results