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Riluzole-Rasagiline Hybrids: Toward the Development of Multi-Target-Directed Ligands for Amyotrophic Lateral Sclerosis.
Albertini C, Salerno A, Atzeni S, Uliassi E, Massenzio F, Maruca A, Rocca R, Mecava M, Silva FSG, Mena D, Valente P, Duarte AI, Chavarria D, Bissaro M, Moro S, Federico S, Spalluto G, Soukup O, Borges F, Alcaro S, Monti B, Oliveira PJ, Menéndez JC, Bolognesi ML. Albertini C, et al. Among authors: menendez jc. ACS Chem Neurosci. 2022 Aug 3;13(15):2252-2260. doi: 10.1021/acschemneuro.2c00261. Epub 2022 Jul 22. ACS Chem Neurosci. 2022. PMID: 35868251 Free PMC article.
A Fluorescent Styrylquinoline with Combined Therapeutic and Diagnostic Activities against Alzheimer's and Prion Diseases.
Staderini M, Aulić S, Bartolini M, Tran HN, González-Ruiz V, Pérez DI, Cabezas N, Martínez A, Martín MA, Andrisano V, Legname G, Menéndez JC, Bolognesi ML. Staderini M, et al. Among authors: menendez jc. ACS Med Chem Lett. 2012 Dec 28;4(2):225-9. doi: 10.1021/ml3003605. eCollection 2013 Feb 14. ACS Med Chem Lett. 2012. PMID: 24900645 Free PMC article.
ITH14001, a CGP37157-Nimodipine Hybrid Designed to Regulate Calcium Homeostasis and Oxidative Stress, Exerts Neuroprotection in Cerebral Ischemia.
Buendia I, Tenti G, Michalska P, Méndez-López I, Luengo E, Satriani M, Padín-Nogueira F, López MG, Ramos MT, García AG, Menéndez JC, León R. Buendia I, et al. Among authors: menendez jc. ACS Chem Neurosci. 2017 Jan 18;8(1):67-81. doi: 10.1021/acschemneuro.6b00181. Epub 2016 Nov 22. ACS Chem Neurosci. 2017. PMID: 27731633
Tacripyrimidines, the first tacrine-dihydropyrimidine hybrids, as multi-target-directed ligands for Alzheimer's disease.
Chioua M, Buzzi E, Moraleda I, Iriepa I, Maj M, Wnorowski A, Giovannini C, Tramarin A, Portali F, Ismaili L, López-Alvarado P, Bolognesi ML, Jóźwiak K, Menéndez JC, Marco-Contelles J, Bartolini M. Chioua M, et al. Among authors: menendez jc. Eur J Med Chem. 2018 Jul 15;155:839-846. doi: 10.1016/j.ejmech.2018.06.044. Epub 2018 Jun 19. Eur J Med Chem. 2018. PMID: 29958119
Neuroprotective Action of Multitarget 7-Aminophenanthridin-6(5H)-one Derivatives against Metal-Induced Cell Death and Oxidative Stress in SN56 Cells.
Moyano P, Vicente-Zurdo D, Blázquez-Barbadillo C, Menéndez JC, González JF, Rosales-Conrado N, Del Pino J. Moyano P, et al. Among authors: menendez jc. ACS Chem Neurosci. 2021 Sep 15;12(18):3358-3372. doi: 10.1021/acschemneuro.1c00333. Epub 2021 Aug 30. ACS Chem Neurosci. 2021. PMID: 34460227 Free PMC article.
Bifunctional carbazole derivatives for simultaneous therapy and fluorescence imaging in prion disease murine cell models.
Staderini M, Vanni S, Baldeschi AC, Giachin G, Zattoni M, Celauro L, Ferracin C, Bistaffa E, Moda F, Pérez DI, Martínez A, Martín MA, Martín-Cámara O, Cores Á, Bianchini G, Kammerer R, Menéndez JC, Legname G, Bolognesi ML. Staderini M, et al. Among authors: menendez jc. Eur J Med Chem. 2023 Jan 5;245(Pt 1):114923. doi: 10.1016/j.ejmech.2022.114923. Epub 2022 Nov 15. Eur J Med Chem. 2023. PMID: 36423450 Free article.
Discovery of a class of diketopiperazines as antiprion compounds.
Bolognesi ML, Ai Tran HN, Staderini M, Monaco A, López-Cobeñas A, Bongarzone S, Biarnés X, López-Alvarado P, Cabezas N, Caramelli M, Carloni P, Menéndez JC, Legname G. Bolognesi ML, et al. Among authors: menendez jc. ChemMedChem. 2010 Aug 2;5(8):1324-34. doi: 10.1002/cmdc.201000133. ChemMedChem. 2010. PMID: 20540064
140 results