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Sepsis expands a CD39+ plasmablast population that promotes immunosuppression via adenosine-mediated inhibition of macrophage antimicrobial activity.
Nascimento DC, Viacava PR, Ferreira RG, Damaceno MA, Piñeros AR, Melo PH, Donate PB, Toller-Kawahisa JE, Zoppi D, Veras FP, Peres RS, Menezes-Silva L, Caetité D, Oliveira AER, Castro ÍMS, Kauffenstein G, Nakaya HI, Borges MC, Zamboni DS, Fonseca DM, Paschoal JAR, Cunha TM, Quesniaux V, Linden J, Cunha FQ, Ryffel B, Alves-Filho JC. Nascimento DC, et al. Among authors: melo ph. Immunity. 2021 Sep 14;54(9):2024-2041.e8. doi: 10.1016/j.immuni.2021.08.005. Epub 2021 Sep 1. Immunity. 2021. PMID: 34473957 Free article.
Neutrophil Extracellular Traps Induce Organ Damage during Experimental and Clinical Sepsis.
Czaikoski PG, Mota JM, Nascimento DC, Sônego F, Castanheira FV, Melo PH, Scortegagna GT, Silva RL, Barroso-Sousa R, Souto FO, Pazin-Filho A, Figueiredo F, Alves-Filho JC, Cunha FQ. Czaikoski PG, et al. Among authors: melo ph. PLoS One. 2016 Feb 5;11(2):e0148142. doi: 10.1371/journal.pone.0148142. eCollection 2016. PLoS One. 2016. PMID: 26849138 Free PMC article.
The Atypical Chemokine Receptor ACKR2 is Protective Against Sepsis.
Castanheira FVES, Borges V, Sônego F, Kanashiro A, Donate PB, Melo PH, Pallas K, Russo RC, Amaral FA, Teixeira MM, Ramalho FS, Cunha TM, Liew FY, Alves-Filho JC, Graham GJ, Cunha FQ. Castanheira FVES, et al. Among authors: melo ph. Shock. 2018 Jun;49(6):682-689. doi: 10.1097/SHK.0000000000000969. Shock. 2018. PMID: 29589840
Galectin-3 aggravates experimental polymicrobial sepsis by impairing neutrophil recruitment to the infectious focus.
Ferreira RG, Rodrigues LC, Nascimento DC, Kanashiro A, Melo PH, Borges VF, Gozzi A, da Silva Prado D, Borges MC, Ramalho FS, Stowell SR, Cummings RD, Dias-Baruffi M, Cunha FQ, Alves-Filho JC. Ferreira RG, et al. Among authors: melo ph. J Infect. 2018 Nov;77(5):391-397. doi: 10.1016/j.jinf.2018.06.010. Epub 2018 Jul 4. J Infect. 2018. PMID: 30226191
HBP/O-GlcNAcylation Metabolic Axis Regulates Bone Resorption Outcome.
Taira TM, Ramos-Junior ES, Melo PH, Costa-Silva CC, Alteen MG, Vocadlo DJ, Dias WB, Cunha FQ, Alves-Filho JC, Søe K, Fukada SY. Taira TM, et al. Among authors: melo ph. J Dent Res. 2023 Apr;102(4):440-449. doi: 10.1177/00220345221141043. Epub 2023 Feb 7. J Dent Res. 2023. PMID: 36749069
S100A9 Drives the Chronification of Psoriasiform Inflammation by Inducing IL-23/Type 3 Immunity.
Silva de Melo BM, Veras FP, Zwicky P, Lima D, Ingelfinger F, Martins TV, da Silva Prado D, Schärli S, Publio G, Hiroki CH, Melo PH, Saraiva A, Norbiato T, Lima L, Ryffel B, Vogl T, Roth J, Waisman A, Nakaya HI, da Silva Souza C, Cunha FQ, Cunha TM, Becher B, Alves-Filho JC. Silva de Melo BM, et al. Among authors: melo ph. J Invest Dermatol. 2023 Sep;143(9):1678-1688.e8. doi: 10.1016/j.jid.2023.02.026. Epub 2023 Mar 13. J Invest Dermatol. 2023. PMID: 36921684
33 results