Melnick AM - Search Results

1

Clinical and Biological Subtypes of B-cell Lymphoma Revealed by Microenvironmental Signatures.

Kotlov N, Bagaev A, Revuelta MV, Phillip JM, Cacciapuoti MT, Antysheva Z, Svekolkin V, Tikhonova E, Miheecheva N, Kuzkina N, Nos G, Tabbo F, Frenkel F, Ghione P, Tsiper M, Almog N, Fowler N, Melnick AM, Leonard JP, Inghirami G, Cerchietti L. Kotlov N, et al. Among authors: melnick am. Cancer Discov. 2021 Jun;11(6):1468-1489. doi: 10.1158/2159-8290.CD-20-0839. Epub 2021 Feb 4. Cancer Discov. 2021. PMID: 33541860 Free PMC article.

2

Specific peptide interference reveals BCL6 transcriptional and oncogenic mechanisms in B-cell lymphoma cells.

Polo JM, Dell'Oso T, Ranuncolo SM, Cerchietti L, Beck D, Da Silva GF, Prive GG, Licht JD, Melnick A. Polo JM, et al. Nat Med. 2004 Dec;10(12):1329-35. doi: 10.1038/nm1134. Epub 2004 Nov 7. Nat Med. 2004. PMID: 15531890

3

Transcriptional signature with differential expression of BCL6 target genes accurately identifies BCL6-dependent diffuse large B cell lymphomas.

Polo JM, Juszczynski P, Monti S, Cerchietti L, Ye K, Greally JM, Shipp M, Melnick A. Polo JM, et al. Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3207-12. doi: 10.1073/pnas.0611399104. Epub 2007 Feb 20. Proc Natl Acad Sci U S A. 2007. PMID: 17360630 Free PMC article.

4

Sequential transcription factor targeting for diffuse large B-cell lymphomas.

Cerchietti LC, Polo JM, Da Silva GF, Farinha P, Shaknovich R, Gascoyne RD, Dowdy SF, Melnick A. Cerchietti LC, et al. Cancer Res. 2008 May 1;68(9):3361-9. doi: 10.1158/0008-5472.CAN-07-5817. Cancer Res. 2008. PMID: 18451163 Free PMC article.

5

B-cell lymphoma 6 and the molecular pathogenesis of diffuse large B-cell lymphoma.

Ci W, Polo JM, Melnick A. Ci W, et al. Curr Opin Hematol. 2008 Jul;15(4):381-90. doi: 10.1097/MOH.0b013e328302c7df. Curr Opin Hematol. 2008. PMID: 18536578 Free PMC article. Review.

6

A peptomimetic inhibitor of BCL6 with potent antilymphoma effects in vitro and in vivo.

Cerchietti LC, Yang SN, Shaknovich R, Hatzi K, Polo JM, Chadburn A, Dowdy SF, Melnick A. Cerchietti LC, et al. Blood. 2009 Apr 9;113(15):3397-405. doi: 10.1182/blood-2008-07-168773. Epub 2008 Oct 16. Blood. 2009. PMID: 18927431 Free PMC article.

7

Outcome of deferred initial therapy in mantle-cell lymphoma.

Martin P, Chadburn A, Christos P, Weil K, Furman RR, Ruan J, Elstrom R, Niesvizky R, Ely S, Diliberto M, Melnick A, Knowles DM, Chen-Kiang S, Coleman M, Leonard JP. Martin P, et al. J Clin Oncol. 2009 Mar 10;27(8):1209-13. doi: 10.1200/JCO.2008.19.6121. Epub 2009 Feb 2. J Clin Oncol. 2009. PMID: 19188674

8

The BCL6 transcriptional program features repression of multiple oncogenes in primary B cells and is deregulated in DLBCL.

Ci W, Polo JM, Cerchietti L, Shaknovich R, Wang L, Yang SN, Ye K, Farinha P, Horsman DE, Gascoyne RD, Elemento O, Melnick A. Ci W, et al. Blood. 2009 May 28;113(22):5536-48. doi: 10.1182/blood-2008-12-193037. Epub 2009 Mar 23. Blood. 2009. PMID: 19307668 Free PMC article.

9

A purine scaffold Hsp90 inhibitor destabilizes BCL-6 and has specific antitumor activity in BCL-6-dependent B cell lymphomas.

Cerchietti LC, Lopes EC, Yang SN, Hatzi K, Bunting KL, Tsikitas LA, Mallik A, Robles AI, Walling J, Varticovski L, Shaknovich R, Bhalla KN, Chiosis G, Melnick A. Cerchietti LC, et al. Nat Med. 2009 Dec;15(12):1369-76. doi: 10.1038/nm.2059. Epub 2009 Nov 22. Nat Med. 2009. PMID: 19966776 Free PMC article.

10

DNA methylation signatures identify biologically distinct subtypes in acute myeloid leukemia.

Figueroa ME, Lugthart S, Li Y, Erpelinck-Verschueren C, Deng X, Christos PJ, Schifano E, Booth J, van Putten W, Skrabanek L, Campagne F, Mazumdar M, Greally JM, Valk PJ, Löwenberg B, Delwel R, Melnick A. Figueroa ME, et al. Cancer Cell. 2010 Jan 19;17(1):13-27. doi: 10.1016/j.ccr.2009.11.020. Epub 2010 Jan 7. Cancer Cell. 2010. PMID: 20060365 Free PMC article.

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