Melnick A - Search Results

1

Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation.

Figueroa ME, Abdel-Wahab O, Lu C, Ward PS, Patel J, Shih A, Li Y, Bhagwat N, Vasanthakumar A, Fernandez HF, Tallman MS, Sun Z, Wolniak K, Peeters JK, Liu W, Choe SE, Fantin VR, Paietta E, Löwenberg B, Licht JD, Godley LA, Delwel R, Valk PJ, Thompson CB, Levine RL, Melnick A. Figueroa ME, et al. Among authors: melnick a. Cancer Cell. 2010 Dec 14;18(6):553-67. doi: 10.1016/j.ccr.2010.11.015. Epub 2010 Dec 9. Cancer Cell. 2010. PMID: 21130701 Free PMC article.

2

Reduced and altered DNA-binding and transcriptional properties of the PLZF-retinoic acid receptor-alpha chimera generated in t(11;17)-associated acute promyelocytic leukemia.

Licht JD, Shaknovich R, English MA, Melnick A, Li JY, Reddy JC, Dong S, Chen SJ, Zelent A, Waxman S. Licht JD, et al. Among authors: melnick a. Oncogene. 1996 Jan 18;12(2):323-36. Oncogene. 1996. PMID: 8570209

3

The promyelocytic leukemia zinc finger protein affects myeloid cell growth, differentiation, and apoptosis.

Shaknovich R, Yeyati PL, Ivins S, Melnick A, Lempert C, Waxman S, Zelent A, Licht JD. Shaknovich R, et al. Among authors: melnick a. Mol Cell Biol. 1998 Sep;18(9):5533-45. doi: 10.1128/MCB.18.9.5533. Mol Cell Biol. 1998. PMID: 9710637 Free PMC article.

4

Deconstructing a disease: RARalpha, its fusion partners, and their roles in the pathogenesis of acute promyelocytic leukemia.

Melnick A, Licht JD. Melnick A, et al. Blood. 1999 May 15;93(10):3167-215. Blood. 1999. PMID: 10233871 Free article. Review. No abstract available.

5

The promyelocytic leukemia zinc finger (PLZF) protein binds DNA in a high molecular weight complex associated with cdc2 kinase.

Ball HJ, Melnick A, Shaknovich R, Kohanski RA, Licht JD. Ball HJ, et al. Among authors: melnick a. Nucleic Acids Res. 1999 Oct 15;27(20):4106-13. doi: 10.1093/nar/27.20.4106. Nucleic Acids Res. 1999. PMID: 10497277 Free PMC article.

6

Identification of novel chromosomal rearrangements in acute myelogenous leukemia involving loci on chromosome 2p23, 15q22 and 17q21.

Melnick A, Fruchtman S, Zelent A, Liu M, Huang Q, Boczkowska B, Calasanz M, Fernandez A, Licht JD, Najfeld V. Melnick A, et al. Leukemia. 1999 Oct;13(10):1534-8. doi: 10.1038/sj.leu.2401513. Leukemia. 1999. PMID: 10516754

7

The ETO protein disrupted in t(8;21)-associated acute myeloid leukemia is a corepressor for the promyelocytic leukemia zinc finger protein.

Melnick AM, Westendorf JJ, Polinger A, Carlile GW, Arai S, Ball HJ, Lutterbach B, Hiebert SW, Licht JD. Melnick AM, et al. Mol Cell Biol. 2000 Mar;20(6):2075-86. doi: 10.1128/MCB.20.6.2075-2086.2000. Mol Cell Biol. 2000. PMID: 10688654 Free PMC article.

8

In-depth mutational analysis of the promyelocytic leukemia zinc finger BTB/POZ domain reveals motifs and residues required for biological and transcriptional functions.

Melnick A, Ahmad KF, Arai S, Polinger A, Ball H, Borden KL, Carlile GW, Prive GG, Licht JD. Melnick A, et al. Mol Cell Biol. 2000 Sep;20(17):6550-67. doi: 10.1128/MCB.20.17.6550-6567.2000. Mol Cell Biol. 2000. PMID: 10938130 Free PMC article.

9

AML-1/ETO fusion protein is a dominant negative inhibitor of transcriptional repression by the promyelocytic leukemia zinc finger protein.

Melnick A, Carlile GW, McConnell MJ, Polinger A, Hiebert SW, Licht JD. Melnick A, et al. Blood. 2000 Dec 1;96(12):3939-47. Blood. 2000. PMID: 11090081 Free article.

10

Translocations of the RARalpha gene in acute promyelocytic leukemia.

Zelent A, Guidez F, Melnick A, Waxman S, Licht JD. Zelent A, et al. Among authors: melnick a. Oncogene. 2001 Oct 29;20(49):7186-203. doi: 10.1038/sj.onc.1204766. Oncogene. 2001. PMID: 11704847 Review.

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