Mellor CL - Search Results

1

The identification of nuclear receptors associated with hepatic steatosis to develop and extend adverse outcome pathways.

Mellor CL, Steinmetz FP, Cronin MT. Mellor CL, et al. Crit Rev Toxicol. 2016 Feb;46(2):138-52. doi: 10.3109/10408444.2015.1089471. Epub 2015 Oct 9. Crit Rev Toxicol. 2016. PMID: 26451809 Review.

2

Development of an in Silico Profiler for Mitochondrial Toxicity.

Nelms MD, Mellor CL, Cronin MT, Madden JC, Enoch SJ. Nelms MD, et al. Among authors: mellor cl. Chem Res Toxicol. 2015 Oct 19;28(10):1891-902. doi: 10.1021/acs.chemrestox.5b00275. Epub 2015 Sep 24. Chem Res Toxicol. 2015. PMID: 26375963

3

Using Molecular Initiating Events to Develop a Structural Alert Based Screening Workflow for Nuclear Receptor Ligands Associated with Hepatic Steatosis.

Mellor CL, Steinmetz FP, Cronin MT. Mellor CL, et al. Chem Res Toxicol. 2016 Feb 15;29(2):203-12. doi: 10.1021/acs.chemrestox.5b00480. Epub 2016 Feb 2. Chem Res Toxicol. 2016. PMID: 26787004 Free article.

4

Screening Chemicals for Receptor-Mediated Toxicological and Pharmacological Endpoints: Using Public Data to Build Screening Tools within a KNIME Workflow.

Steinmetz FP, Mellor CL, Meinl T, Cronin MT. Steinmetz FP, et al. Among authors: mellor cl. Mol Inform. 2015 Feb;34(2-3):171-8. doi: 10.1002/minf.201400188. Epub 2015 Feb 20. Mol Inform. 2015. PMID: 27490039

5

In Silico Prediction of Organ Level Toxicity: Linking Chemistry to Adverse Effects.

Cronin MTD, Enoch SJ, Mellor CL, Przybylak KR, Richarz AN, Madden JC. Cronin MTD, et al. Among authors: mellor cl. Toxicol Res. 2017 Jul;33(3):173-182. doi: 10.5487/TR.2017.33.3.173. Epub 2017 Jul 15. Toxicol Res. 2017. PMID: 28744348 Free PMC article. Review.

6

A critical review of adverse effects to the kidney: mechanisms, data sources, and in silico tools to assist prediction.

Pletz J, Enoch SJ, Jais DM, Mellor CL, Pawar G, Firman JW, Madden JC, Webb SD, Tagliati CA, Cronin MTD. Pletz J, et al. Among authors: mellor cl. Expert Opin Drug Metab Toxicol. 2018 Dec;14(12):1225-1253. doi: 10.1080/17425255.2018.1539076. Epub 2018 Nov 25. Expert Opin Drug Metab Toxicol. 2018. PMID: 30345815 Review.

7

Molecular fingerprint-derived similarity measures for toxicological read-across: Recommendations for optimal use.

Mellor CL, Marchese Robinson RL, Benigni R, Ebbrell D, Enoch SJ, Firman JW, Madden JC, Pawar G, Yang C, Cronin MTD. Mellor CL, et al. Regul Toxicol Pharmacol. 2019 Feb;101:121-134. doi: 10.1016/j.yrtph.2018.11.002. Epub 2018 Nov 20. Regul Toxicol Pharmacol. 2019. PMID: 30468762 Free article.

8

In Silico Identification of Chemicals Capable of Binding to the Ecdysone Receptor.

Mellor CL, Tollefsen KE, LaLone C, Cronin MTD, Firman JW. Mellor CL, et al. Environ Toxicol Chem. 2020 Jul;39(7):1438-1450. doi: 10.1002/etc.4733. Epub 2020 Jun 4. Environ Toxicol Chem. 2020. PMID: 32335943 Free PMC article.

9

A Mechanistic Framework for Integrating Chemical Structure and High-Throughput Screening Results to Improve Toxicity Predictions.

Nelms MD, Mellor CL, Enoch SJ, Judson RS, Patlewicz G, Richard AM, Madden JM, Cronin MTD, Edwards SW. Nelms MD, et al. Among authors: mellor cl. Comput Toxicol. 2018 Nov;8:1-12. doi: 10.1016/j.comtox.2018.08.003. Comput Toxicol. 2018. PMID: 36779220 Free PMC article.

10

Effectiveness and cost effectiveness of counselling in primary care.

Bower P, Rowland N, Mellor Cl, Heywood P, Godfrey C, Hardy R. Bower P, et al. Among authors: mellor cl. Cochrane Database Syst Rev. 2002;(1):CD001025. doi: 10.1002/14651858.CD001025. Cochrane Database Syst Rev. 2002. PMID: 11869583 Updated. Review.

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