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The HIF target MAFF promotes tumor invasion and metastasis through IL11 and STAT3 signaling.
Moon EJ, Mello SS, Li CG, Chi JT, Thakkar K, Kirkland JG, Lagory EL, Lee IJ, Diep AN, Miao Y, Rafat M, Vilalta M, Castellini L, Krieg AJ, Graves EE, Attardi LD, Giaccia AJ. Moon EJ, et al. Among authors: mello ss. Nat Commun. 2021 Jul 14;12(1):4308. doi: 10.1038/s41467-021-24631-6. Nat Commun. 2021. PMID: 34262028 Free PMC article.
Not all p53 gain-of-function mutants are created equal.
Mello SS, Attardi LD. Mello SS, et al. Cell Death Differ. 2013 Jul;20(7):855-7. doi: 10.1038/cdd.2013.53. Cell Death Differ. 2013. PMID: 23749181 Free PMC article. No abstract available.
Unravelling mechanisms of p53-mediated tumour suppression.
Bieging KT, Mello SS, Attardi LD. Bieging KT, et al. Among authors: mello ss. Nat Rev Cancer. 2014 May;14(5):359-70. doi: 10.1038/nrc3711. Epub 2014 Apr 17. Nat Rev Cancer. 2014. PMID: 24739573 Free PMC article.
The p53 Target Gene SIVA Enables Non-Small Cell Lung Cancer Development.
Van Nostrand JL, Brisac A, Mello SS, Jacobs SB, Luong R, Attardi LD. Van Nostrand JL, et al. Among authors: mello ss. Cancer Discov. 2015 Jun;5(6):622-35. doi: 10.1158/2159-8290.CD-14-0921. Epub 2015 Mar 26. Cancer Discov. 2015. PMID: 25813352 Free PMC article.
Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma.
Mazur PK, Herner A, Mello SS, Wirth M, Hausmann S, Sánchez-Rivera FJ, Lofgren SM, Kuschma T, Hahn SA, Vangala D, Trajkovic-Arsic M, Gupta A, Heid I, Noël PB, Braren R, Erkan M, Kleeff J, Sipos B, Sayles LC, Heikenwalder M, Heßmann E, Ellenrieder V, Esposito I, Jacks T, Bradner JE, Khatri P, Sweet-Cordero EA, Attardi LD, Schmid RM, Schneider G, Sage J, Siveke JT. Mazur PK, et al. Among authors: mello ss. Nat Med. 2015 Oct;21(10):1163-71. doi: 10.1038/nm.3952. Epub 2015 Sep 21. Nat Med. 2015. PMID: 26390243 Free PMC article.
Neat1 is a p53-inducible lincRNA essential for transformation suppression.
Mello SS, Sinow C, Raj N, Mazur PK, Bieging-Rolett K, Broz DK, Imam JFC, Vogel H, Wood LD, Sage J, Hirose T, Nakagawa S, Rinn J, Attardi LD. Mello SS, et al. Genes Dev. 2017 Jun 1;31(11):1095-1108. doi: 10.1101/gad.284661.116. Epub 2017 Jul 11. Genes Dev. 2017. PMID: 28698299 Free PMC article.
A p53 Super-tumor Suppressor Reveals a Tumor Suppressive p53-Ptpn14-Yap Axis in Pancreatic Cancer.
Mello SS, Valente LJ, Raj N, Seoane JA, Flowers BM, McClendon J, Bieging-Rolett KT, Lee J, Ivanochko D, Kozak MM, Chang DT, Longacre TA, Koong AC, Arrowsmith CH, Kim SK, Vogel H, Wood LD, Hruban RH, Curtis C, Attardi LD. Mello SS, et al. Cancer Cell. 2017 Oct 9;32(4):460-473.e6. doi: 10.1016/j.ccell.2017.09.007. Cancer Cell. 2017. PMID: 29017057 Free PMC article.
Deciphering p53 signaling in tumor suppression.
Mello SS, Attardi LD. Mello SS, et al. Curr Opin Cell Biol. 2018 Apr;51:65-72. doi: 10.1016/j.ceb.2017.11.005. Epub 2017 Nov 28. Curr Opin Cell Biol. 2018. PMID: 29195118 Free PMC article. Review.
52 results