Mellgren G - Search Results

1

Effect of Genetic Variability in 20 Pharmacogenes on Concentrations of Tamoxifen and Its Metabolites.

Chen Y, Marcath LA, Eliassen FM, Lende TH, Soiland H, Mellgren G, Helland T, Hertz DL. Chen Y, et al. Among authors: mellgren g. J Pers Med. 2021 Jun 4;11(6):507. doi: 10.3390/jpm11060507. J Pers Med. 2021. PMID: 34199712 Free PMC article.

2

Downregulation of steroid receptor coactivator-2 modulates estrogen-responsive genes and stimulates proliferation of mcf-7 breast cancer cells.

Fenne IS, Helland T, Flågeng MH, Dankel SN, Mellgren G, Sagen JV. Fenne IS, et al. Among authors: mellgren g. PLoS One. 2013 Jul 30;8(7):e70096. doi: 10.1371/journal.pone.0070096. Print 2013. PLoS One. 2013. PMID: 23936147 Free PMC article.

3

Serum concentrations of tamoxifen and its metabolites increase with age during steady-state treatment.

Lien EA, Søiland H, Lundgren S, Aas T, Steen VM, Mellgren G, Gjerde J. Lien EA, et al. Among authors: mellgren g. Breast Cancer Res Treat. 2013 Sep;141(2):243-8. doi: 10.1007/s10549-013-2677-9. Epub 2013 Sep 1. Breast Cancer Res Treat. 2013. PMID: 23996142 Free PMC article.

4

The active tamoxifen metabolite endoxifen (4OHNDtam) strongly down-regulates cytokeratin 6 (CK6) in MCF-7 breast cancer cells.

Helland T, Gjerde J, Dankel S, Fenne IS, Skartveit L, Drangevåg A, Bozickovic O, Flågeng MH, Søiland H, Mellgren G, Lien EA. Helland T, et al. Among authors: mellgren g. PLoS One. 2015 Apr 13;10(4):e0122339. doi: 10.1371/journal.pone.0122339. eCollection 2015. PLoS One. 2015. PMID: 25867603 Free PMC article.

5

Cyclin C interacts with steroid receptor coactivator 2 and upregulates cell cycle genes in MCF-7 cells.

Bozickovic O, Hoang T, Fenne IS, Helland T, Skartveit L, Ouchida M, Mellgren G, Sagen JV. Bozickovic O, et al. Among authors: mellgren g. Biochim Biophys Acta. 2015 Oct;1853(10 Pt A):2383-91. doi: 10.1016/j.bbamcr.2015.05.016. Epub 2015 May 16. Biochim Biophys Acta. 2015. PMID: 25986860 Free article.

6

Angiopoietin-like protein 8/betatrophin as a new determinant of type 2 diabetes remission after bariatric surgery.

Ejarque M, Borlaug M, Vilarrasa N, Martinez-Perez B, Llauradó G, Megía A, Helland T, Gutierrez C, Serena C, Folkestad O, Nuñez-Roa C, Roche K, Casajoana A, Fradera R, González-Clemente JM, López M, Mohn AC, Nedrebø BG, Nogueiras R, Mellgren G, Fernø J, Fernández-Veledo S, Vendrell J. Ejarque M, et al. Among authors: mellgren g. Transl Res. 2017 Jun;184:35-44.e4. doi: 10.1016/j.trsl.2017.03.001. Epub 2017 Mar 9. Transl Res. 2017. PMID: 28347650 Clinical Trial.

7

Serum concentrations of active tamoxifen metabolites predict long-term survival in adjuvantly treated breast cancer patients.

Helland T, Henne N, Bifulco E, Naume B, Borgen E, Kristensen VN, Kvaløy JT, Lash TL, Alnæs GIG, van Schaik RH, Janssen EAM, Hustad S, Lien EA, Mellgren G, Søiland H. Helland T, et al. Among authors: mellgren g. Breast Cancer Res. 2017 Nov 28;19(1):125. doi: 10.1186/s13058-017-0916-4. Breast Cancer Res. 2017. PMID: 29183390 Free PMC article.

8

A novel SRC-2-dependent regulation of epithelial-mesenchymal transition in breast cancer cells.

Bozickovic O, Skartveit L, Engelsen AST, Helland T, Jonsdottir K, Flågeng MH, Fenne IS, Janssen E, Lorens JB, Bjørkhaug L, Sagen JV, Mellgren G. Bozickovic O, et al. Among authors: mellgren g. J Steroid Biochem Mol Biol. 2019 Jan;185:57-70. doi: 10.1016/j.jsbmb.2018.07.011. Epub 2018 Jul 23. J Steroid Biochem Mol Biol. 2019. PMID: 30048685

9

Drug monitoring of tamoxifen metabolites predicts vaginal dryness and verifies a low discontinuation rate from the Norwegian Prescription Database.

Helland T, Hagen KB, Haugstøyl ME, Kvaløy JT, Lunde S, Lode K, Lind RA, Gripsrud BH, Jonsdottir K, Gjerde J, Bifulco E, Hustad S, Jonassen J, Aas T, Lende TH, Lien EA, Janssen EAM, Søiland H, Mellgren G. Helland T, et al. Among authors: mellgren g. Breast Cancer Res Treat. 2019 Aug;177(1):185-195. doi: 10.1007/s10549-019-05294-w. Epub 2019 May 29. Breast Cancer Res Treat. 2019. PMID: 31144152

10

First-in-human pharmacokinetics of tamoxifen and its metabolites in the milk of a lactating mother: a case study.

Peccatori FA, Codacci-Pisanelli G, Mellgren G, Buonomo B, Baldassarre E, Lien EA, Bifulco E, Hustad S, Zachariassen E, Johansson H, Helland T. Peccatori FA, et al. Among authors: mellgren g. ESMO Open. 2020 Oct;5(5):e000859. doi: 10.1136/esmoopen-2020-000859. ESMO Open. 2020. PMID: 33115771 Free PMC article.

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