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447 results

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Page 1
High mobility group box 1 orchestrates tissue regeneration via CXCR4.
Tirone M, Tran NL, Ceriotti C, Gorzanelli A, Canepari M, Bottinelli R, Raucci A, Di Maggio S, Santiago C, Mellado M, Saclier M, François S, Careccia G, He M, De Marchis F, Conti V, Ben Larbi S, Cuvellier S, Casalgrandi M, Preti A, Chazaud B, Al-Abed Y, Messina G, Sitia G, Brunelli S, Bianchi ME, Vénéreau E. Tirone M, et al. Among authors: mellado m. J Exp Med. 2018 Jan 2;215(1):303-318. doi: 10.1084/jem.20160217. Epub 2017 Dec 4. J Exp Med. 2018. PMID: 29203538 Free PMC article.
HMGB1 promotes recruitment of inflammatory cells to damaged tissues by forming a complex with CXCL12 and signaling via CXCR4.
Schiraldi M, Raucci A, Muñoz LM, Livoti E, Celona B, Venereau E, Apuzzo T, De Marchis F, Pedotti M, Bachi A, Thelen M, Varani L, Mellado M, Proudfoot A, Bianchi ME, Uguccioni M. Schiraldi M, et al. Among authors: mellado m. J Exp Med. 2012 Mar 12;209(3):551-63. doi: 10.1084/jem.20111739. Epub 2012 Feb 27. J Exp Med. 2012. PMID: 22370717 Free PMC article.
The Role of the CXCL12/CXCR4/ACKR3 Axis in Autoimmune Diseases.
García-Cuesta EM, Santiago CA, Vallejo-Díaz J, Juarranz Y, Rodríguez-Frade JM, Mellado M. García-Cuesta EM, et al. Among authors: mellado m. Front Endocrinol (Lausanne). 2019 Aug 27;10:585. doi: 10.3389/fendo.2019.00585. eCollection 2019. Front Endocrinol (Lausanne). 2019. PMID: 31507535 Free PMC article. Review.
Epithelial chemokine CXCL14 synergizes with CXCL12 via allosteric modulation of CXCR4.
Collins PJ, McCully ML, Martínez-Muñoz L, Santiago C, Wheeldon J, Caucheteux S, Thelen S, Cecchinato V, Laufer JM, Purvanov V, Monneau YR, Lortat-Jacob H, Legler DF, Uguccioni M, Thelen M, Piguet V, Mellado M, Moser B. Collins PJ, et al. Among authors: mellado m. FASEB J. 2017 Jul;31(7):3084-3097. doi: 10.1096/fj.201700013R. Epub 2017 Mar 30. FASEB J. 2017. PMID: 28360196 Free PMC article.
M., Purvanov, V., Monneau, Y. R., Lortat-Jacob, H., Legler, D. F., Uguccioni, M., Thelen, M., Piguet, V., Mellado, M., Moser, B. Epithelial chemokine CXCL14 synergizes with CXCL12 via allosteric modulation of CXCR4....
M., Purvanov, V., Monneau, Y. R., Lortat-Jacob, H., Legler, D. F., Uguccioni, M., Thelen, M., Piguet, V., Mellado …
Separating Actin-Dependent Chemokine Receptor Nanoclustering from Dimerization Indicates a Role for Clustering in CXCR4 Signaling and Function.
Martínez-Muñoz L, Rodríguez-Frade JM, Barroso R, Sorzano CÓS, Torreño-Pina JA, Santiago CA, Manzo C, Lucas P, García-Cuesta EM, Gutierrez E, Barrio L, Vargas J, Cascio G, Carrasco YR, Sánchez-Madrid F, García-Parajo MF, Mellado M. Martínez-Muñoz L, et al. Among authors: mellado m. Mol Cell. 2018 Apr 5;70(1):106-119.e10. doi: 10.1016/j.molcel.2018.02.034. Mol Cell. 2018. PMID: 29625032 Free article.
CCR5/CD4/CXCR4 oligomerization prevents HIV-1 gp120IIIB binding to the cell surface.
Martínez-Muñoz L, Barroso R, Dyrhaug SY, Navarro G, Lucas P, Soriano SF, Vega B, Costas C, Muñoz-Fernández MÁ, Santiago C, Rodríguez Frade JM, Franco R, Mellado M. Martínez-Muñoz L, et al. Among authors: mellado m. Proc Natl Acad Sci U S A. 2014 May 13;111(19):E1960-9. doi: 10.1073/pnas.1322887111. Epub 2014 Apr 28. Proc Natl Acad Sci U S A. 2014. PMID: 24778234 Free PMC article.
Altered CXCR4 dynamics at the cell membrane impairs directed cell migration in WHIM syndrome patients.
García-Cuesta EM, Rodríguez-Frade JM, Gardeta SR, D'Agostino G, Martínez P, Soler Palacios B, Cascio G, Wolf T, Mateos N, Ayala-Bueno R, Santiago CA, Lucas P, Llorente L, Allende LM, González-Granado LI, Martín-Cófreces N, Roda-Navarro P, Sallusto F, Sánchez-Madrid F, García-Parajo MF, Martínez-Muñoz L, Mellado M. García-Cuesta EM, et al. Among authors: mellado m. Proc Natl Acad Sci U S A. 2022 May 24;119(21):e2119483119. doi: 10.1073/pnas.2119483119. Epub 2022 May 19. Proc Natl Acad Sci U S A. 2022. PMID: 35588454 Free PMC article.
447 results