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Synthesis of Novel Nicotinic Ligands with Multimodal Action: Targeting Acetylcholine α4β2, Dopamine and Serotonin Transporters.
González-Gutiérrez JP, Pessoa-Mahana HA, Iturriaga-Vásquez PE, Reyes-Parada MI, Guerra-Díaz NE, Hodar-Salazar M, Viscarra F, Paillali P, Núñez-Vivanco G, Lorca-Carvajal MA, Mella-Raipán J, Zúñiga MC. González-Gutiérrez JP, et al. Among authors: mella raipan j. Molecules. 2019 Oct 22;24(20):3808. doi: 10.3390/molecules24203808. Molecules. 2019. PMID: 31652614 Free PMC article.
Synthesis, Docking, 3-D-Qsar, and Biological Assays of Novel Indole Derivatives Targeting Serotonin Transporter, Dopamine D2 Receptor, and Mao-A Enzyme: In the Pursuit for Potential Multitarget Directed Ligands.
Cerda-Cavieres C, Quiroz G, Iturriaga-Vásquez P, Rodríguez-Lavado J, Alarcón-Espósito J, Saitz C, Pessoa-Mahana CD, Chung H, Araya-Maturana R, Mella-Raipán J, Cabezas D, Ojeda-Gómez C, Reyes-Parada M, Pessoa-Mahana H. Cerda-Cavieres C, et al. Among authors: mella raipan j. Molecules. 2020 Oct 10;25(20):4614. doi: 10.3390/molecules25204614. Molecules. 2020. PMID: 33050524 Free PMC article.
Synthesis, in vitro evaluation and molecular docking of a new class of indolylpropyl benzamidopiperazines as dual AChE and SERT ligands for Alzheimer's disease.
Rodríguez-Lavado J, Gallardo-Garrido C, Mallea M, Bustos V, Osorio R, Hödar-Salazar M, Chung H, Araya-Maturana R, Lorca M, Pessoa-Mahana CD, Mella-Raipán J, Saitz C, Jaque P, Reyes-Parada M, Iturriaga-Vásquez P, Pessoa-Mahana H. Rodríguez-Lavado J, et al. Among authors: mella raipan j. Eur J Med Chem. 2020 Jul 15;198:112368. doi: 10.1016/j.ejmech.2020.112368. Epub 2020 Apr 29. Eur J Med Chem. 2020. PMID: 32388114
Design, synthesis, biological evaluation and binding mode modeling of benzimidazole derivatives targeting the cannabinoid receptor type 1.
Espinosa-Bustos C, Lagos CF, Romero-Parra J, Zárate AM, Mella-Raipán J, Pessoa-Mahana H, Recabarren-Gajardo G, Iturriaga-Vásquez P, Tapia RA, Pessoa-Mahana CD. Espinosa-Bustos C, et al. Among authors: mella raipan j. Arch Pharm (Weinheim). 2015 Feb;348(2):81-8. doi: 10.1002/ardp.201400201. Epub 2015 Jan 13. Arch Pharm (Weinheim). 2015. PMID: 25641513
Synthesis, binding assays, cytotoxic activity and docking studies of benzimidazole and benzothiophene derivatives with selective affinity for the CB2 cannabinoid receptor.
Romero-Parra J, Mella-Raipán J, Palmieri V, Allarà M, Torres MJ, Pessoa-Mahana H, Iturriaga-Vásquez P, Escobar R, Faúndez M, Di Marzo V, Pessoa-Mahana CD. Romero-Parra J, et al. Among authors: mella raipan j. Eur J Med Chem. 2016 Nov 29;124:17-35. doi: 10.1016/j.ejmech.2016.08.005. Epub 2016 Aug 5. Eur J Med Chem. 2016. PMID: 27560280
Novel N-Arylsulfonylindoles Targeted as Ligands of the 5-HT6 Receptor. Insights on the Influence of C-5 Substitution on Ligand Affinity.
Arrieta-Rodríguez L, Espinoza-Rosales D, Vera G, Cho YH, Cabezas D, Vásquez-Velásquez D, Mella-Raipán J, Lagos CF, Recabarren-Gajardo G. Arrieta-Rodríguez L, et al. Among authors: mella raipan j. Pharmaceuticals (Basel). 2021 Jun 1;14(6):528. doi: 10.3390/ph14060528. Pharmaceuticals (Basel). 2021. PMID: 34206083 Free PMC article.
15 results