Mella J - Search Results

1

A New Kind of Quinonic-Antibiotic Useful Against Multidrug-Resistant S. aureus and E. faecium Infections.

Campanini-Salinas J, Andrades-Lagos J, Gonzalez Rocha G, Choquesillo-Lazarte D, Bollo Dragnic S, Faúndez M, Alarcón P, Silva F, Vidal R, Salas-Huenuleo E, Kogan M, Mella J, Recabarren Gajardo G, Vásquez-Velásquez D. Campanini-Salinas J, et al. Among authors: mella j. Molecules. 2018 Jul 19;23(7):1776. doi: 10.3390/molecules23071776. Molecules. 2018. PMID: 30029513 Free PMC article.

2

Combined CoMFA and CoMSIA 3D-QSAR study of benzimidazole and benzothiophene derivatives with selective affinity for the CB2 cannabinoid receptor.

Romero-Parra J, Chung H, Tapia RA, Faúndez M, Morales-Verdejo C, Lorca M, Lagos CF, Di Marzo V, David Pessoa-Mahana C, Mella J. Romero-Parra J, et al. Among authors: mella j. Eur J Pharm Sci. 2017 Apr 1;101:1-10. doi: 10.1016/j.ejps.2017.01.037. Epub 2017 Jan 28. Eur J Pharm Sci. 2017. PMID: 28137469

3

2D-QSAR and 3D-QSAR/CoMSIA Studies on a Series of (R)-2-((2-(1H-Indol-2-yl)ethyl)amino)-1-Phenylethan-1-ol with Human β₃-Adrenergic Activity.

Apablaza G, Montoya L, Morales-Verdejo C, Mellado M, Cuellar M, Lagos CF, Soto-Delgado J, Chung H, Pessoa-Mahana CD, Mella J. Apablaza G, et al. Among authors: mella j. Molecules. 2017 Mar 5;22(3):404. doi: 10.3390/molecules22030404. Molecules. 2017. PMID: 28273884 Free PMC article.

4

Structure-Activity Relationships Based on 3D-QSAR CoMFA/CoMSIA and Design of Aryloxypropanol-Amine Agonists with Selectivity for the Human β3-Adrenergic Receptor and Anti-Obesity and Anti-Diabetic Profiles.

Lorca M, Morales-Verdejo C, Vásquez-Velásquez D, Andrades-Lagos J, Campanini-Salinas J, Soto-Delgado J, Recabarren-Gajardo G, Mella J. Lorca M, et al. Among authors: mella j. Molecules. 2018 May 16;23(5):1191. doi: 10.3390/molecules23051191. Molecules. 2018. PMID: 29772697 Free PMC article.

5

Promising 2,6,9-Trisubstituted Purine Derivatives for Anticancer Compounds: Synthesis, 3D-QSAR, and Preliminary Biological Assays.

O Salas C, Zarate AM, Kryštof V, Mella J, Faundez M, Brea J, Loza MI, Brito I, Hendrychová D, Jorda R, Cabrera AR, Tapia RA, Espinosa-Bustos C. O Salas C, et al. Among authors: mella j. Int J Mol Sci. 2019 Dec 25;21(1):161. doi: 10.3390/ijms21010161. Int J Mol Sci. 2019. PMID: 31881717 Free PMC article.

6

Design, Synthesis, In Silico Studies and Inhibitory Activity towards Bcr-Abl, BTK and FLT3-ITD of New 2,6,9-Trisubstituted Purine Derivatives as Potential Agents for the Treatment of Leukaemia.

Bertrand J, Dostálová H, Kryštof V, Jorda R, Delgado T, Castro-Alvarez A, Mella J, Cabezas D, Faúndez M, Espinosa-Bustos C, Salas CO. Bertrand J, et al. Among authors: mella j. Pharmaceutics. 2022 Jun 17;14(6):1294. doi: 10.3390/pharmaceutics14061294. Pharmaceutics. 2022. PMID: 35745866 Free PMC article.

7

Cytotoxic Activity, Topoisomerase I Inhibition and In Silico Studies of New Sesquiterpene-aryl Ester Derivatives of (-) Drimenol.

Araque I, Ramírez J, Vergara R, Mella J, Aránguiz P, Espinoza L, Vera W, Montenegro I, Salas CO, Villena J, Cuellar MA. Araque I, et al. Among authors: mella j. Molecules. 2023 May 8;28(9):3959. doi: 10.3390/molecules28093959. Molecules. 2023. PMID: 37175368 Free PMC article.

8

Design, Synthesis, and Structure-Activity Relationship Studies of New Quinone Derivatives as Antibacterial Agents.

Andrades-Lagos J, Campanini-Salinas J, Pedreros-Riquelme A, Mella J, Choquesillo-Lazarte D, Zamora PP, Pessoa-Mahana H, Burbulis I, Vásquez-Velásquez D. Andrades-Lagos J, et al. Among authors: mella j. Antibiotics (Basel). 2023 Jun 16;12(6):1065. doi: 10.3390/antibiotics12061065. Antibiotics (Basel). 2023. PMID: 37370384 Free PMC article.

9

QSAR Studies, Synthesis, and Biological Evaluation of New Pyrimido-Isoquinolin-Quinone Derivatives against Methicillin-Resistant Staphylococcus aureus.

Andrades-Lagos J, Campanini-Salinas J, Sabadini G, Andrade V, Mella J, Vásquez-Velásquez D. Andrades-Lagos J, et al. Among authors: mella j. Pharmaceuticals (Basel). 2023 Nov 17;16(11):1621. doi: 10.3390/ph16111621. Pharmaceuticals (Basel). 2023. PMID: 38004487 Free PMC article.

10

A combined CoMFA and CoMSIA 3D-QSAR study of benzamide type antibacterial inhibitors of the FtsZ protein in drug-resistant Staphylococcus aureus.

Andrades J, Campanini J, Vásquez D, Silvestri C, Morales C, Romero J, Mella J. Andrades J, et al. Among authors: mella j. SAR QSAR Environ Res. 2015;26(11):925-42. doi: 10.1080/1062936X.2015.1095798. Epub 2015 Oct 27. SAR QSAR Environ Res. 2015. PMID: 26505124

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