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Differentiation of crescent-forming kidney progenitor cells into podocytes attenuates severe glomerulonephritis in mice.
Melica ME, Antonelli G, Semeraro R, Angelotti ML, Lugli G, Landini S, Ravaglia F, Regina G, Conte C, De Chiara L, Peired AJ, Mazzinghi B, Donati M, Molli A, Steiger S, Magi A, Bartalucci N, Raglianti V, Guzzi F, Maggi L, Annunziato F, Burger A, Lazzeri E, Anders HJ, Lasagni L, Romagnani P. Melica ME, et al. Sci Transl Med. 2022 Aug 10;14(657):eabg3277. doi: 10.1126/scitranslmed.abg3277. Epub 2022 Aug 10. Sci Transl Med. 2022. PMID: 35947676 Free PMC article.
Endocycle-related tubular cell hypertrophy and progenitor proliferation recover renal function after acute kidney injury.
Lazzeri E, Angelotti ML, Peired A, Conte C, Marschner JA, Maggi L, Mazzinghi B, Lombardi D, Melica ME, Nardi S, Ronconi E, Sisti A, Antonelli G, Becherucci F, De Chiara L, Guevara RR, Burger A, Schaefer B, Annunziato F, Anders HJ, Lasagni L, Romagnani P. Lazzeri E, et al. Among authors: melica me. Nat Commun. 2018 Apr 9;9(1):1344. doi: 10.1038/s41467-018-03753-4. Nat Commun. 2018. PMID: 29632300 Free PMC article.
CXCL12 blockade preferentially regenerates lost podocytes in cortical nephrons by targeting an intrinsic podocyte-progenitor feedback mechanism.
Romoli S, Angelotti ML, Antonelli G, Kumar Vr S, Mulay SR, Desai J, Anguiano Gomez L, Thomasova D, Eulberg D, Klussmann S, Melica ME, Conte C, Lombardi D, Lasagni L, Anders HJ, Romagnani P. Romoli S, et al. Among authors: melica me. Kidney Int. 2018 Dec;94(6):1111-1126. doi: 10.1016/j.kint.2018.08.013. Epub 2018 Oct 29. Kidney Int. 2018. PMID: 30385042 Free PMC article.
Crystal Clots as Therapeutic Target in Cholesterol Crystal Embolism.
Shi C, Kim T, Steiger S, Mulay SR, Klinkhammer BM, Bäuerle T, Melica ME, Romagnani P, Möckel D, Baues M, Yang L, Brouns SLN, Heemskerk JWM, Braun A, Lammers T, Boor P, Anders HJ. Shi C, et al. Among authors: melica me. Circ Res. 2020 Apr 10;126(8):e37-e52. doi: 10.1161/CIRCRESAHA.119.315625. Epub 2020 Feb 24. Circ Res. 2020. PMID: 32089086 Free article.
Acute kidney injury promotes development of papillary renal cell adenoma and carcinoma from renal progenitor cells.
Peired AJ, Antonelli G, Angelotti ML, Allinovi M, Guzzi F, Sisti A, Semeraro R, Conte C, Mazzinghi B, Nardi S, Melica ME, De Chiara L, Lazzeri E, Lasagni L, Lottini T, Landini S, Giglio S, Mari A, Di Maida F, Antonelli A, Porpiglia F, Schiavina R, Ficarra V, Facchiano D, Gacci M, Serni S, Carini M, Netto GJ, Roperto RM, Magi A, Christiansen CF, Rotondi M, Liapis H, Anders HJ, Minervini A, Raspollini MR, Romagnani P. Peired AJ, et al. Among authors: melica me. Sci Transl Med. 2020 Mar 25;12(536):eaaw6003. doi: 10.1126/scitranslmed.aaw6003. Sci Transl Med. 2020. PMID: 32213630
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