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A GWAS in the pandemic epicenter highlights the severe COVID-19 risk locus introgressed by Neanderthals.
Breno M, Noris M, Rubis N, Parvanova AI, Martinetti D, Gamba S, Liguori L, Mele C, Piras R, Orisio S, Valoti E, Alberti M, Diadei O, Bresin E, Rigoldi M, Prandini S, Gamba T, Stucchi N, Carrara F, Daina E, Benigni A, Remuzzi G; ORIGIN study group. Breno M, et al. Among authors: mele c. iScience. 2023 Aug 16;26(10):107629. doi: 10.1016/j.isci.2023.107629. eCollection 2023 Oct 20. iScience. 2023. PMID: 37731612 Free PMC article.
Hemolytic uremic syndrome.
Mele C, Remuzzi G, Noris M. Mele C, et al. Semin Immunopathol. 2014 Jul;36(4):399-420. doi: 10.1007/s00281-014-0416-x. Epub 2014 Feb 14. Semin Immunopathol. 2014. PMID: 24526222 Review.
Complement gene variants determine the risk of immunoglobulin-associated MPGN and C3 glomerulopathy and predict long-term renal outcome.
Iatropoulos P, Noris M, Mele C, Piras R, Valoti E, Bresin E, Curreri M, Mondo E, Zito A, Gamba S, Bettoni S, Murer L, Fremeaux-Bacchi V, Vivarelli M, Emma F, Daina E, Remuzzi G. Iatropoulos P, et al. Among authors: mele c. Mol Immunol. 2016 Mar;71:131-142. doi: 10.1016/j.molimm.2016.01.010. Epub 2016 Feb 16. Mol Immunol. 2016. PMID: 26895476
Rare Functional Variants in Complement Genes and Anti-FH Autoantibodies-Associated aHUS.
Valoti E, Alberti M, Iatropoulos P, Piras R, Mele C, Breno M, Cremaschi A, Bresin E, Donadelli R, Alizzi S, Amoroso A, Benigni A, Remuzzi G, Noris M. Valoti E, et al. Among authors: mele c. Front Immunol. 2019 May 1;10:853. doi: 10.3389/fimmu.2019.00853. eCollection 2019. Front Immunol. 2019. PMID: 31118930 Free PMC article.
Molecular Studies and an ex vivo Complement Assay on Endothelium Highlight the Genetic Complexity of Atypical Hemolytic Uremic Syndrome: The Case of a Pedigree With a Null CD46 Variant.
Piras R, Iatropoulos P, Bresin E, Todeschini M, Gastoldi S, Valoti E, Alberti M, Mele C, Galbusera M, Cuccarolo P, Benigni A, Remuzzi G, Noris M. Piras R, et al. Among authors: mele c. Front Med (Lausanne). 2020 Nov 3;7:579418. doi: 10.3389/fmed.2020.579418. eCollection 2020. Front Med (Lausanne). 2020. PMID: 33224962 Free PMC article.
203 results