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Multi-target-directed ligands to combat neurodegenerative diseases.
Cavalli A, Bolognesi ML, Minarini A, Rosini M, Tumiatti V, Recanatini M, Melchiorre C. Cavalli A, et al. Among authors: melchiorre c. J Med Chem. 2008 Feb 14;51(3):347-72. doi: 10.1021/jm7009364. Epub 2008 Jan 9. J Med Chem. 2008. PMID: 18181565 Review. No abstract available.
Structure-activity relationships of methoctramine-related polyamines as muscular nicotinic receptor noncompetitive antagonists. 2. Role of polymethylene chain lengths separating amine functions and of substituents on the terminal nitrogen atoms.
Rosini M, Bixel MG, Marucci G, Budriesi R, Krauss M, Bolognesi ML, Minarini A, Tumiatti V, Hucho F, Melchiorre C. Rosini M, et al. Among authors: melchiorre c. J Med Chem. 2002 Apr 25;45(9):1860-78. doi: 10.1021/jm011067f. J Med Chem. 2002. PMID: 11960498
Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 2. Role of the substituents on the phenyl ring and nitrogen atoms of caproctamine.
Tumiatti V, Rosini M, Bartolini M, Cavalli A, Marucci G, Andrisano V, Angeli P, Banzi R, Minarini A, Recanatini M, Melchiorre C. Tumiatti V, et al. Among authors: melchiorre c. J Med Chem. 2003 Mar 13;46(6):954-66. doi: 10.1021/jm021055+. J Med Chem. 2003. PMID: 12620072
Rational approach to discover multipotent anti-Alzheimer drugs.
Rosini M, Andrisano V, Bartolini M, Bolognesi ML, Hrelia P, Minarini A, Tarozzi A, Melchiorre C. Rosini M, et al. Among authors: melchiorre c. J Med Chem. 2005 Jan 27;48(2):360-3. doi: 10.1021/jm049112h. J Med Chem. 2005. PMID: 15658850
171 results