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Page 1
Clinically relevant molecular hallmarks of PFA ependymomas display intratumoral heterogeneity and correlate with tumor morphology.
Gödicke S, Kresbach C, Ehlert M, Obrecht D, Altendorf L, Hack K, von Hoff K, Carén H, Melcher V, Kerl K, Englinger B, Filbin M, Pajtler KW, Gojo J, Pietsch T, Rutkowski S, Schüller U. Gödicke S, et al. Among authors: melcher v. Acta Neuropathol. 2024 Jan 24;147(1):23. doi: 10.1007/s00401-023-02682-x. Acta Neuropathol. 2024. PMID: 38265527 Free PMC article.
Mitochondrial DNA mutations in Medulloblastoma.
Funke VLE, Sandmann S, Melcher V, Seggewiss J, Horvath J, Jäger N, Kool M, Jones DTW, Pfister SM, Milde T, Rutkowski S, Mynarek M, Varghese J, Sträter R, Rust S, Seelhöfer A, Reunert J, Fiedler B, Schüller U, Marquardt T, Kerl K. Funke VLE, et al. Among authors: melcher v. Acta Neuropathol Commun. 2023 Jul 27;11(1):124. doi: 10.1186/s40478-023-01602-0. Acta Neuropathol Commun. 2023. PMID: 37501103 Free PMC article.
Group-specific cellular metabolism in Medulloblastoma.
Funke VLE, Walter C, Melcher V, Wei L, Sandmann S, Hotfilder M, Varghese J, Jäger N, Kool M, Jones DTW, Pfister SM, Milde T, Mynarek M, Rutkowski S, Seggewiss J, Jeising D, de Faria FW, Marquardt T, Albert TK, Schüller U, Kerl K. Funke VLE, et al. Among authors: melcher v. J Transl Med. 2023 Jun 5;21(1):363. doi: 10.1186/s12967-023-04211-6. J Transl Med. 2023. PMID: 37277823 Free PMC article.
Single-cell transcriptomics identifies potential cells of origin of MYC rhabdoid tumors.
Graf M, Interlandi M, Moreno N, Holdhof D, Göbel C, Melcher V, Mertins J, Albert TK, Kastrati D, Alfert A, Holsten T, de Faria F, Meisterernst M, Rossig C, Warmuth-Metz M, Nowak J, Meyer Zu Hörste G, Mayère C, Nef S, Johann P, Frühwald MC, Dugas M, Schüller U, Kerl K. Graf M, et al. Among authors: melcher v. Nat Commun. 2022 Mar 22;13(1):1544. doi: 10.1038/s41467-022-29152-4. Nat Commun. 2022. PMID: 35318328 Free PMC article.
An extracellular vesicle-related gene expression signature identifies high-risk patients in medulloblastoma.
Albert TK, Interlandi M, Sill M, Graf M, Moreno N, Menck K, Rohlmann A, Melcher V, Korbanka S, Meyer Zu Hörste G, Lautwein T, Frühwald MC, Krebs CF, Holdhof D, Schoof M, Bleckmann A, Missler M, Dugas M, Schüller U, Jäger N, Pfister SM, Kerl K. Albert TK, et al. Among authors: melcher v. Neuro Oncol. 2021 Apr 12;23(4):586-598. doi: 10.1093/neuonc/noaa254. Neuro Oncol. 2021. PMID: 33175161 Free PMC article.
Macrophage-tumor cell interaction promotes ATRT progression and chemoresistance.
Melcher V, Graf M, Interlandi M, Moreno N, de Faria FW, Kim SN, Kastrati D, Korbanka S, Alfert A, Gerß J, Meyer Zu Hörste G, Hartmann W, Frühwald MC, Dugas M, Schüller U, Hasselblatt M, Albert TK, Kerl K. Melcher V, et al. Acta Neuropathol. 2020 May;139(5):913-936. doi: 10.1007/s00401-019-02116-7. Epub 2019 Dec 17. Acta Neuropathol. 2020. PMID: 31848709