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The collagen receptor uPARAP/Endo180 as a novel target for antibody-drug conjugate mediated treatment of mesenchymal and leukemic cancers.
Nielsen CF, van Putten SM, Lund IK, Melander MC, Nørregaard KS, Jürgensen HJ, Reckzeh K, Christensen KR, Ingvarsen SZ, Gårdsvoll H, Jensen KE, Hamerlik P, Engelholm LH, Behrendt N. Nielsen CF, et al. Among authors: melander mc. Oncotarget. 2017 Jul 4;8(27):44605-44624. doi: 10.18632/oncotarget.17883. Oncotarget. 2017. PMID: 28574834 Free PMC article.
Targeting a novel bone degradation pathway in primary bone cancer by inactivation of the collagen receptor uPARAP/Endo180.
Engelholm LH, Melander MC, Hald A, Persson M, Madsen DH, Jürgensen HJ, Johansson K, Nielsen C, Nørregaard KS, Ingvarsen SZ, Kjaer A, Trovik CS, Laerum OD, Bugge TH, Eide J, Behrendt N. Engelholm LH, et al. Among authors: melander mc. J Pathol. 2016 Jan;238(1):120-33. doi: 10.1002/path.4661. Epub 2015 Nov 30. J Pathol. 2016. PMID: 26466547
Targeting a single function of the multifunctional matrix metalloprotease MT1-MMP: impact on lymphangiogenesis.
Ingvarsen S, Porse A, Erpicum C, Maertens L, Jürgensen HJ, Madsen DH, Melander MC, Gårdsvoll H, Høyer-Hansen G, Noel A, Holmbeck K, Engelholm LH, Behrendt N. Ingvarsen S, et al. Among authors: melander mc. J Biol Chem. 2013 Apr 12;288(15):10195-204. doi: 10.1074/jbc.M112.447169. Epub 2013 Feb 14. J Biol Chem. 2013. PMID: 23413031 Free PMC article.
The non-phagocytic route of collagen uptake: a distinct degradation pathway.
Madsen DH, Ingvarsen S, Jürgensen HJ, Melander MC, Kjøller L, Moyer A, Honoré C, Madsen CA, Garred P, Burgdorf S, Bugge TH, Behrendt N, Engelholm LH. Madsen DH, et al. Among authors: melander mc. J Biol Chem. 2011 Jul 29;286(30):26996-7010. doi: 10.1074/jbc.M110.208033. Epub 2011 Jun 7. J Biol Chem. 2011. PMID: 21652704 Free PMC article.
14 results