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Novel lectin-based chimeric antigen receptors target Gb3-positive tumour cells.
Meléndez AV, Velasco Cárdenas RM, Lagies S, Strietz J, Siukstaite L, Thomas OS, Tomisch J, Weber W, Kammerer B, Römer W, Minguet S. Meléndez AV, et al. Cell Mol Life Sci. 2022 Sep 12;79(10):513. doi: 10.1007/s00018-022-04524-7. Cell Mol Life Sci. 2022. PMID: 36097202 Free PMC article.
Bacterial lectin BambL acts as a B cell superantigen.
Frensch M, Jäger C, Müller PF, Tadić A, Wilhelm I, Wehrum S, Diedrich B, Fischer B, Meléndez AV, Dengjel J, Eibel H, Römer W. Frensch M, et al. Among authors: melendez av. Cell Mol Life Sci. 2021 Dec;78(24):8165-8186. doi: 10.1007/s00018-021-04009-z. Epub 2021 Nov 3. Cell Mol Life Sci. 2021. PMID: 34731252 Free PMC article.
Harnessing CD3 diversity to optimize CAR T cells.
Velasco Cárdenas RM, Brandl SM, Meléndez AV, Schlaak AE, Buschky A, Peters T, Beier F, Serrels B, Taromi S, Raute K, Hauri S, Gstaiger M, Lassmann S, Huppa JB, Boerries M, Andrieux G, Bengsch B, Schamel WW, Minguet S. Velasco Cárdenas RM, et al. Among authors: melendez av. Nat Immunol. 2023 Dec;24(12):2135-2149. doi: 10.1038/s41590-023-01658-z. Epub 2023 Nov 6. Nat Immunol. 2023. PMID: 37932456 Free PMC article.